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4-Maleimidobutyric acid N-hydroxysuccinimide ester

SIAL/63175 - ≥98.0% (HPLC)

Synonym: 4-Maleimidobutyric acid N-succinimidyl ester; N-(γ-Maleimidobutyryloxy)succinimide; N-Succinimidyl 4-maleimidobutyrate; GMBS

CAS Number: 80307-12-6
Empirical Formula (Hill Notation): C12H12N2O6
Molecular Weight: 280.23
MDL Number: MFCD00036817
Linear Formula: C12H12N2O6
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-63175-25MG-F 25 mg
 DISCONTINUED  
45-63175-100MG-F 100 mg
 $360.00
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assay ≥98.0% (HPLC)
functional group NHS ester
InChI 1S/C12H12N2O6/c15-8-3-4-9(16)13(8)7-1-2-12(19)20-14-10(17)5-6-11(14)18/h3-4H,1-2,5-7H2
InChI key PVGATNRYUYNBHO-UHFFFAOYSA-N
mp 123-129 °C
Quality Level 100 
reaction suitability reagent type: linker
SMILES string O=C1N(CCCC(ON2C(CCC2=O)=O)=O)C(C=C1)=O
storage temp. 2-8°C
Application: A heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Provides a 7-atom linker.
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98.0% (HPLC)
mp 123-129 °C
Storage Temp. 2-8°C
UNSPSC 12352106

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