6-Maleimidohexanoic acid N-hydroxysuccinimide ester

SIAL/63177 - ≥98.0% (HPLC)

Synonym: 6-Maleimidocaproic acid N-succinimidyl ester; N-(ε-Maleimidocaproyloxy)succinimide; N-Succinimidyl 6-maleimidocaproate; EMCS

CAS Number: 55750-63-5
Empirical Formula (Hill Notation): C₁₄H₁₆N₂O₆
Molecular Weight: 308.29
MDL Number: MFCD00043043
Linear Formula: C₁₄H₁₆N₂O₆
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-63177-25MG	25 mg	$221.00 1/EAAdd To Favorites	Add To Favorites
45-63177-100MG	100 mg	$0.00 1/EA CALL FOR PRICEAdd To Favorites	Add To Favorites

assay	≥98.0% (HPLC)
form	solid
functional group	NHS ester
InChI	1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2
InChI key	VLARLSIGSPVYHX-UHFFFAOYSA-N
mp	67-73 °C
	70-73 °C (lit.)
Quality Level	200
reaction suitability	reagent type: linker
SMILES string	O=C(ON(C(CC1)=O)C1=O)CCCCCN2C(C=CC2=O)=O
storage temp.	−20°C

Application:	6-Maleimidohexanoic acid N-hydroxysuccinimide ester is a heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.
Other Notes:	Reagent for cross-linking and immobilisation of proteins
Packaging:	Bottomless glass bottle. Contents are inside inserted fused cone.

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98.0% (HPLC)
mp	67-73 °C; 70-73 °C (lit.)
Storage Temp.	−20°C
UNSPSC	12352106