5-Maleimido-eosin

SIAL/63184 - for fluorescence, ≥93% (HPLC)

Synonym: EMA; Eosin-5-maleimide; Eosin-5-maleimide

CAS Number: 150322-02-4
Empirical Formula (Hill Notation): C₂₄H₉Br₄NO₇
Molecular Weight: 742.95
MDL Number: MFCD07437936
Linear Formula: C₂₄H₉Br₄NO₇
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-63184-10MG	10 mg	$398.00 1/EA		Add To Favorites
45-63184-25MG	25 mg	$673.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥93% (HPLC)
grade	for fluorescence
InChI	1S/C24H9Br4NO7/c25-13-6-11-21(17(27)19(13)32)35-22-12(7-14(26)20(33)18(22)28)24(11)10-2-1-8(5-9(10)23(34)36-24)29-15(30)3-4-16(29)31/h1-7,32-33H
InChI key	YRCLWXRIEYQTAV-UHFFFAOYSA-N
Quality Level	100
SMILES string	Oc1c(Br)cc2c(Oc3c(Br)c(O)c(Br)cc3C24OC(=O)c5cc(ccc45)N6C(=O)C=CC6=O)c1Br
storage temp.	2-8°C

Application:	Eosin-5-maleimide has been used as a fluorescent probe for the human erythrocyte band 3 protein. (2) It is widely used as a diagnostic probe for the laboratory detection of hereditary spherocytosis (HS) by flow cytometry. (3) The eosin-5-maleimide binding test was done to analyze the effect of alectinib (first line of treatment) for anaplastic lymphoma kinase (ALK).
General description:	5-Maleimido-eosin, also known as EMA or Eosin-5-maleimide, is a fluorescent binding agent. The 5-Maleimido-eosin binding test measures the EMA-labeled cells reduced mean channel fluorescence (MCF) reading.
Other Notes:	Triplet probe. Measurement of rotational diffusion of protein in solution and in membranes, including myosin and pyruvate dehydrogenase

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥93% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352207

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