2-Methyltetrahydrofuran
SIAL/673277 - BioRenewable, anhydrous, ≥99%, Inhibitor-free
Synonym: 2-MeTHF; Tetrahydro-
CAS Number: 96-47-9
Empirical Formula (Hill Notation): C5H10O
Molecular Weight: 86.13
EC Number: 202-507-4
MDL Number: MFCD00005367
Linear Formula: C5H10O
Product Type: Chemical
Anhydrous, Sureseal
Anhydrous, Sureseal
12 Principles of Green Chemistry: Principle 5—Safer Solvents and Auxiliaries. This product utilizes reduced volumes of auxiliary substances that are less hazardous.
12 Principles of Green Chemistry: Principle 7—A raw material or feedstock should be renewable rather than depleting whenever technically and economically practicable.
| assay | ≥99% |
| bp | 78-80 °C (lit.) |
| density | 0.86 g/mL at 25 °C (lit.) |
| evapn. residue | ≤0.0003% |
| expl. lim. | 0.34-6.3 % (lit.) |
| form | liquid |
| grade | anhydrous |
| greener alternative category |  , Aligned , Aligned |
| greener alternative product characteristics | Safer Solvents and Auxiliaries Use of Renewable Feedstocks Learn more about the Principles of Green Chemistry . |
| impurities | ≤0.002% water |
| ≤0.005% water (100 mL pkg) | |
| InChI | 1S/C5H10O/c1-5-3-2-4-6-5/ |
| InChI key | JWUJQDFVADABEY-UHFFFAOYSA |
| mp | -136 °C (lit.) |
| Quality Level | 100 |
| refractive index | n |
| SMILES string | CC1CCCO1 |
| sustainability | Greener Alternative Product |
| Application: | 2-Methyltetrahydrofuran may be used as a solvent for phosphatidylserine synthesis. It may be used as an alternative solvent to:• Dimethyl sulfoxide (DMSO) or methyl tert-butyl ether (MTBE) in the C-C bond forming reactions catalyzed by lyase enzyme. • Tetrahydrofuran (THF) in the reaction between Grignard reagents and carbonyl compounds. • Methylene chloride in some biphasic reactions. Green Alternatives to DCM and THF from Renewable Resources Organic Solar Cells  2-Methyltetrahydrofuran (2-MeTHF): A Biomass-Derived Solvent with Broad Application in Organic Chemistry |
| Features and Benefits: | Greener alternative for THF, DCM, DMSO, and MTBE |
| General description: | We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is a biorenewable and thus aligns with "Safer Solvents and Auxiliaries" and "Use of Renewable Feedstocks". Click here for more information. 2-Methyltetrahydrofuran (2-MTHF), a 2-methyl substituted tetrahydrofuran, is a biomass derived solvent. It is a potential greener solvent alternative for organic synthesis. It shows resistance to reduction by lithium making it a promising candidate as electrolytes in lithium batteries. Its polarity and Lewis base strength is intermediate between tetrahydrofuran (THF) and diethyl ether. The ring opening reaction of 2-MTHF has been studied using acid chloride and iodide. |
| Packaging: | 1, 2 L in Sure/Seal™ |
| Packaging: | 100, 12×100 mL in Sure/Seal™ |
| Packaging: | 200 L in Pure-Pac™ 2 |
| Symbol |    GHS02,GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H225 - H302 - H315 - H318 |
| Precautionary statements | P210 - P233 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338 |
| Hazard Codes | F |
| Risk Statements | 11-22-38-41 |
| Safety Statements | 26-39 |
| RIDADR | UN 2536 3 / PGII |
| WGK Germany | WGK 2 |
| Flash Point(F) | 14.0 °F - closed cup |
| Flash Point(C) | -10.0 °C - closed cup |
| Supplemental Hazard Statements | EUH019 |
| Purity | ≥99% |
| bp | 78-80 °C (lit.) |
| mp | -136 °C (lit.) |
| Density | 0.86 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352005 |