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N-Methyl-N-(trimethylsilyl)trifluoroacetamide

SIAL/69479 - derivatization grade (GC derivatization), LiChropur™, ≥98.5%

Synonym: N-Trimethylsilyl-N-methyl trifluoroacetamide; MSTFA

CAS Number: 24589-78-4
Empirical Formula (Hill Notation): C6H12F3NOSi
Molecular Weight: 199.25
EC Number: 246-331-6
MDL Number: MFCD00000411
Linear Formula: CF3CON(CH3)Si(CH3)3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-69479-10X1ML 1 mL
 $217.00
10/EA		 Add To Favorites
45-69479-5ML 5 mL
 $135.00
1/EA		 Add To Favorites
45-69479-25ML 25 mL
 $403.00
1/EA		 Add To Favorites

 

assay ≥98.5%
  ≥98.5% (GC)
bp 130-132 °C (lit.)
density 1.075 g/mL at 25 °C (lit.)
form liquid
grade derivatization grade (GC derivatization)
InChI 1S/C6H12F3NOSi/c1-10(12(2,3)4)5(11)6(7,8)9/h1-4H3
InChI key MSPCIZMDDUQPGJ-UHFFFAOYSA-N
quality LiChropur™
Quality Level 200 
reaction suitability reagent type: derivatization reagent
reaction type: Silylations
refractive index n20/D 1.38 (lit.)
  n20/D 1.380
SMILES string CN(C(=O)C(F)(F)F)[Si](C)(C)C
storage temp. 2-8°C
technique(s) gas chromatography (GC): suitable
vapor density >1 (vs air)
vapor pressure 8.8 mmHg ( 27 °C)
Application: Learn more in the Product Information 
Application: MSTFA may be used in silylation procedure to detemine steroid hormones 17α-ethinylestradiol (EE2) and estrone using GC-MS. MSTFA along with Trimethylsilyl chloride (TMCS) in eithyl acetate, acetonitrile and dichloromethane solvents leads to formation of trimethylsilyl (TMS) and tert-butyldimethylsilyl (TBS) derivatives.
Application: Suitable for the derivatization of amines, amino acids, carboxyl, hydroxyamines, indolalkylamine, n-nitrosoamino acids, nucleosides, phenolalkylamines, serotonin and tryptamine.
General description: N-Methyl-N-(trimethylsilyl)trifluoroacetamide (MSTFA) is a silylating reagent.
Legal Information: LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
Other Notes: Powerful silylating agent
Other Notes: Reagent for N-acetyl-N, trifluoroacetyl, trimethylsilyl, N-trimethylsilyl-N-trifluoroacetyl, and O-trimethylsilyl (TMS)
Purity ≥98.5% (GC); ≥98.5%
bp 130-132 °C (lit.)
Density 1.075 g/mL at 25 °C (lit.)
Refractive Index n20/D 1.38 (lit.); n20/D 1.380
Storage Temp. 2-8°C
UNSPSC 23151817

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