N-Methyl-N-trimethylsilylacetamide
SIAL/69480 - for GC derivatization, LiChropur™, ≥97.0% (GC)
Synonym: MSA
CAS Number: 7449-74-3
Empirical Formula (Hill Notation): C6H15NOSi
Molecular Weight: 145.27
EC Number: 231-217-0
MDL Number: MFCD00040758
Linear Formula: C6H15NOSi
Product Type: Chemical
| assay | ≥97.0% (GC) |
| bp | 159-161 °C (lit.) |
| density | 0.904 g/mL at 20 °C (lit.) |
| form | liquid |
| grade | for GC derivatization |
| InChI | 1S/C6H15NOSi/c1-6(8)7(2)9 |
| InChI key | QHUOBLDKFGCVCG-UHFFFAOYSA |
| quality | LiChropur™ |
| Quality Level | 100  |
| reaction suitability | reagent type: derivatization reagent reaction type: Silylations |
| refractive index | n |
| SMILES string | CN(C(C)=O)[Si](C)(C)C |
| storage temp. | −20°C |
| technique(s) | gas chromatography (GC): suitable |
| Application: | N-Methyl-N-trimethylsilylacetamide may be used as a derivatizing reagent for the following: • Quantification of the carbohydrate intermediates in glycation systems using gas chromatography coupled to mass spectrometry technique. • Characterization of damaged products of thymine and cytosine formed by the exposure to UV light in a hydrogen peroxide solution using gas chromatography/mass spectrometry with scan mode and selected ion monitoring mode. |
| General description: | N-Methyl-N-trimethylsilylacetamide is a trialkyl-silyl reagent and a versatile derivatizing agent used in gas chromatography (GC). |
| Legal Information: | LiChropur is a trademark of Merck KGaA, Darmstadt, Germany |
| Other Notes: | Powerful silylating agent for polar compounds |
| Symbol |  GHS02 |
| Signal word | Warning |
| Hazard statements | H226 |
| Risk Statements | 10 |
| RIDADR | UN 1993C 3 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 118.4 °F - closed cup |
| Flash Point(C) | 48.0 °C - closed cup |
| Purity | ≥97.0% (GC) |
| bp | 159-161 °C (lit.) |
| Density | 0.904 g/mL at 20 °C (lit.) |
| Refractive Index | n |
| Storage Temp. | −20°C |
| UNSPSC | 12000000 |