Synonym: 4′,5,6,7-Tetrahydroxyflavone 7-glucuronide; 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid; 7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Breviscapin; Scutellarein-7-O-β-D-glucuronide
CAS Number: 27740-01-8
Empirical Formula (Hill Notation): C21H18O12
Molecular Weight: 462.36
MDL Number: MFCD01861503
Linear Formula: C21H18O12
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 73577-10MG
application(s) |
food and beverages |
assay |
≥98.0% (HPLC) |
format |
neat |
grade |
analytical standard |
InChI |
1S/C21H18O12/c22-8-3-1-7(2-4-8)10-5-9(23)13-11(31-10)6-12(14(24)15(13)25)32-21-18(28)16(26)17(27)19(33-21)20(29)30/h1-6,16-19,21-22,24-28H,(H,29,30)/t16-,17-,18+,19-,21+/m0/s1 |
InChI key |
DJSISFGPUUYILV-ZFORQUDYSA-N |
Quality Level |
100 |
shelf life |
limited shelf life, expiry date on the label |
SMILES string |
O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2cc3OC(=CC(=O)c3c(O)c2O)c4ccc(O)cc4 |
storage temp. |
2-8°C |
technique(s) |
gas chromatography (GC): suitable |
|
HPLC: suitable |
Application: |
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
Application: |
Scutellarin may be used as an analytical reference standard for the quantification of the analyte in plasma samples using different chromatography techniques. |
Biochem/physiol Actions: |
Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion model, the compound reduced infarct volume and neurological deficits by increasing eNOS expression while inhibiting the induction of iNOS. |
General description: |
Scutellarin is flavone glucuronide and an active ingredient of breviscapine. It is widely used for the treatment of cerebral infarction, coronary heart disease and angina pectoris. |
Packaging: |
Bottomless glass bottle. Contents are inside inserted fused cone. |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Purity |
≥98.0% (HPLC) |
Storage Temp. |
2-8°C |
UNSPSC |
85151701 |