Trifluoroacetic acid
SIAL/74564 - analytical standard
Synonym: TFA
CAS Number: 76-05-1
Empirical Formula (Hill Notation): C2HF3O2
Molecular Weight: 114.02
EC Number: 200-929-3
MDL Number: MFCD00004169
Linear Formula: CF3COOH
Product Type: Chemical
| application(s) | environmental |
| assay | ≥99.0% (GC) |
| bp | 72.4 °C (lit.) |
| density | 1.489 g/mL at 20 °C (lit.) |
| format | neat |
| grade | analytical standard |
| impurities | ≤0.05% water |
| InChI | 1S/C2HF3O2/c3-2(4,5)1(6)7 |
| InChI key | DTQVDTLACAAQTR-UHFFFAOYSA |
| mp | −15.4 °C (lit.) |
| Quality Level | 100  |
| refractive index | n |
| shelf life | limited shelf life, expiry date on the label |
| SMILES string | OC(C(F)(F)F)=O |
| solubility | H2O: soluble |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable | |
| vapor density | 3.9 (vs air) |
| vapor pressure | 97.5 mmHg ( 20 °C) |
| Application: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
| Application: | Trifluoroacetic acid may be used as a modifier in high performance liquid chromatography mobile phase for protein and peptide separation due to its properties like chromatographic selectivity, high volatility and low ultraviolet light cut-off. Trifluoroacetic acid may be used as an analytical reference standard for the determination of the analyte in water matrices using high-performance liquid chromatography coupled to tandem mass spectrometry. |
| Application: | Trifluoroacetic acid may be used as a modifier in high performance liquid chromatography mobile phase for protein and peptide separation due to its properties like chromatographic selectivity, high volatility and low ultraviolet light cut-off. |
| General description: | Trifluoroacetic acid is a phytotoxic compound belonging to the class of perfluorinated acids (PFAs). It is an environmental contaminant, which contributes to the organo-fluorine burden in surface and ground waters. |
| Symbol |   GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H314 - H332 - H412 |
| Precautionary statements | P261 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | C |
| Risk Statements | 20-35-52/53 |
| Safety Statements | 9-26-27-28-45-61 |
| RIDADR | UN 2699 8 / PGI |
| WGK Germany | WGK 2 |
| Flash Point(F) | 212.0 °F - Pensky-Martens c |
| Flash Point(C) | > 100 °C - Pensky-Martens c |
| Purity | ≥99.0% (GC) |
| bp | 72.4 °C (lit.) |
| mp | −15.4 °C (lit.) |
| Density | 1.489 g/mL at 20 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 41116107 |