Piperine
SIAL/75047 - analytical standard
Synonym: 1-Piperoylpiperidine
CAS Number: 94-62-2
Empirical Formula (Hill Notation): C17H19NO3
Molecular Weight: 285.34
EC Number: 202-348-0
MDL Number: MFCD00005839
Linear Formula: C17H19NO3
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 75047-50MG
| application(s) | cleaning products cosmetics flavors and fragrances food and beverages personal care |
| assay | ≥97.0% (HPLC) |
| format | neat |
| grade | analytical standard |
| InChI | 1S/C17H19NO3/c19-17(18-10 |
| InChI key | MXXWOMGUGJBKIW-YPCIICBESA |
| mp | 131-135 °C (lit.) |
| Quality Level | 100  |
| shelf life | limited shelf life, expiry date on the label |
| SMILES string | O=C(C=CC=Cc1ccc2OCOc2c |
| storage temp. | 2-8°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Application: | Piperine may be used as an analytical reference standard for the quantification of the analyte in: • Human plasma using high-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS). • Piper nigrum extract using reversed phase high pressure liquid chromatographic method with UV detection (RP-HPLC-UV). • Food products using high-performance liquid chromatography with diode array detection (HPLC-DAD). |
| Application: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
| General description: | Piperine is a naturally occurring bioactive alkaloid in pepper, which imparts pungency and bitter flavor to it. It has demonstrated health benefits and exhibits therapeutic properties, which include its role as an antimicrobial, antioxidant, antifungal, immunomodulatory and hepatoprotective agent. The inhibition of drug-metabolizing enzymes in hepatic and pulmonary tissues, and the enhancement of drug bioavailability by this compound are reported. It is also found to play an important role in reducing blood glucose, cholesterol and triglycerides. |
| General description: | Piperine is an amide isolated from the plant, Piper longum. It is a known inhibitor of hepatic and intestinal glucuronidation. Piperine is found to exhibit pharmacological properties like antitumor, antipyretic and anti-inflammatory activities. |
| Symbol |   GHS07,GHS09 |
| Signal word | Warning |
| Hazard statements | H302 - H411 |
| Precautionary statements | P264 - P270 - P273 - P301 + P312 - P391 - P501 |
| Hazard Codes | Xn,N |
| Risk Statements | 22-51/53 |
| Safety Statements | 61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥97.0% (HPLC) |
| mp | 131-135 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 85151701 |