Trimethyl orthobutyrate
SIAL/75571 - purum, ≥97.0% (GC)
Synonym: 1,1,1-
CAS Number: 43083-12-1
Empirical Formula (Hill Notation): C7H16O3
Molecular Weight: 148.20
EC Number: 256-079-9
MDL Number: MFCD00008480
Linear Formula: CH3CH2CH2C(OCH3)3
Product Type: Chemical
assay | ≥97.0% (GC) |
bp | 145-147 °C (lit.) |
density | 0.926 g/mL at 25 °C (lit.) |
form | liquid |
grade | purum |
InChI | 1S/C7H16O3/c1-5-6-7(8-2,9 |
InChI key | JAFMOTJMRSZOJE-UHFFFAOYSA |
Quality Level | 300 ![]() |
refractive index | n |
n |
|
SMILES string | CCCC(OC)(OC)OC |
Application: | Trimethyl orthobutyrate can be used for: • Acylation at OH-9 of N-acetylneuraminic acid and N-glycoloylneuraminic acid to give the corresponding 9-O-acylated derivatives. • Conversion of 2-amino-N-(1-H-benzimidazol-2-yl)b • Preparation of 2-propyl substituted benzimidazoles from 1,2-benzenediamines. It can also be used in the total synthesis of dl-camptothecin, Olmesartan Medoxomil, DE and CDE ring analogs of camptothecin, and homologs of 1,25-dihydroxyvitamin D3. |
Other Notes: | Reagent for preparing cyclic 17,21-methyl orthobutyrates of corticoids |
Symbol | ![]() ![]() |
Signal word | Warning |
Hazard statements | H226 - H315 - H319 - H335 |
Precautionary statements | P210 - P302 + P352 - P305 + P351 + P338 |
Hazard Codes | Xi |
Risk Statements | 10-36/37/38 |
Safety Statements | 26-36 |
RIDADR | UN 3272 3 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | 122.0 °F - closed cup |
Flash Point(C) | 50 °C - closed cup |
Purity | ≥97.0% (GC) |
bp | 145-147 °C (lit.) |
Density | 0.926 g/mL at 25 °C (lit.) |
Refractive Index | n |
UNSPSC | 12352100 |