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2,6-Di-tert-butyl-4-methylphenol

SIAL/75918 - certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Synonym: 2,6-Di-tert-butyl-p-cresol; BHT; Butylated hydroxytoluene; Butylhydroxytoluene; DBPC

CAS Number: 128-37-0
Empirical Formula (Hill Notation): C15H24O
Molecular Weight: 220.35
MDL Number: MFCD00011644
Linear Formula: [(CH3)3C]2C6H2(CH3)OH
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-75918-50MG 50 mg
$109.00
1/EA
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application(s) cleaning products
cosmetics
food and beverages
personal care
autoignition temp. 878 °F
bp 265 °C (lit.)
format neat
grade TraceCERT®
  certified reference material
InChI 1S/C15H24O/c1-10-8-11(14(2,3)4)13(16)12(9-10)15(5,6)7/h8-9,16H,1-7H3
InChI key NLZUEZXRPGMBCV-UHFFFAOYSA-N
manufacturer/tradename Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
mp 69-73 °C (lit.)
product line TraceCERT®
Quality Level 300 
shelf life limited shelf life, expiry date on the label
SMILES string Cc1cc(c(O)c(c1)C(C)(C)C)C(C)(C)C
storage temp. 2-8°C
vapor density 7.6 (vs air)
vapor pressure <0.01 mmHg ( 20 °C)
Application: • Antioxidant and nanoremediation applications: The study highlighted the use of 2,6-Di-tert-butyl-4-methylphenol or BHT in the synthesis of biogenic silver nanoparticles with antioxidant properties, emphasizing its role in environmental remediation and protection against oxidative stress (Silva et al., 2024 ).
• Antioxidant peptides from silk protein: This research demonstrated the antioxidant properties of peptides derived from Bombyx mori, with 2,6-Di-tert-butyl-4-methylphenol possibly serving as a comparative standard in evaluating antioxidant activity, showcasing its importance in food and biochemical research (Chukiatsiri et al., 2024 ).
• Biotechnological production of vitamins: Its role could extend to serving as a standard in optimizing metabolic pathways for the production of other important compounds, like retinol in biotechnology applications, highlighting its utility in industrial microbiology (Ren et al., 2024 ).
General description: This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.
General description: This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. Find all available reference materials for compounds listed in 10/2011 here 
Legal Information: TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany
Symbol GHS09  GHS09
Signal word Warning
Hazard statements H410
Precautionary statements P273
RIDADR UN 3077 9 / PGIII
WGK Germany WGK 2
Flash Point(F) 260.6 °F - open cup
Flash Point(C) 127 °C - open cup
bp 265 °C (lit.)
mp 69-73 °C (lit.)
Storage Temp. 2-8°C
UNSPSC 12352200

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