Pefabloc® SC
SIAL/76307 - analytical standard
Synonym: 4-
CAS Number: 30827-99-7
Empirical Formula (Hill Notation): C8H10FNO2S · HCl
Molecular Weight: 239.69
MDL Number: MFCD00132962
Linear Formula: C8H10FNO2S · HCl
Product Type: Chemical
application(s) | forensics and toxicology pharmaceutical (small molecule) |
assay | ≥95.0% (HPLC) |
form | powder or crystals |
format | neat |
grade | analytical standard |
InChI | 1S/C8H10FNO2S.ClH/c9-13(1 |
InChI key | WRDABNWSWOHGMS-UHFFFAOYSA |
Quality Level | 200 ![]() |
shelf life | 5 yr |
SMILES string | FS(C1=CC=C(CCN)C=C1)(=O)= |
storage temp. | 2-8°C |
technique(s) | gas chromatography (GC): suitable |
HPLC: suitable |
Application: | Pefabloc® SC may be used as an analytical standard in determining the native oligomeric state and substrate specificity of rat NTPDase1 and NTPDase2 after heterologous expression in Xenopus oocytes. It may also be used as an esterase inhibitor, which is added to the whole blood to improve the stability of ciclesonide for the determination of ciclesonide (CIC) and its active metabolite, desisobutyryl-ciclesonide (des-CIC), in human plasma using liquid chromatography-atmospheri |
Application: | Recommended concentrations for use are 0.1-1 mM. |
Application: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
Biochem/physiol Actions: | 4-(2-Aminoethyl)benzenesu |
General description: | Pefabloc® SC is a potent, nontoxic and relatively easy to use, irreversible serine proteinase inhibitor. It is reported to efficiently inhibit the platelet activating factor (PAF)-degrading acetylhydrolase (acetylhydrolase) in both humans and rats. |
General description: | Pefabloc® SC is a trypsin inhibitor, which can be used in the synthesis of its arginine-like analogue, 4-(2-guanidinoethyl)benze |
Legal Information: | Pefabloc is a registered trademark of Pentapharm |
Other Notes: | Potent and irreversible inhibitor of serine proteases; in contrast to PMSF, it is water soluble and non-toxic; Unaffected by albumin |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H315 - H319 |
Precautionary statements | P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313 |
Hazard Codes | C |
Risk Statements | 34 |
Safety Statements | 26-36/37/39-45 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95.0% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 41116107 |