Temozolomide

SIAL/76899 - VETRANAL^®, analytical standard

Synonym: 3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide; 3-Methyl-4-oxo-8-imidazolo[5,1-d][1,2,3,5]tetrazinecarboxamide; 4-Methyl-5-oxo-2,3,4,6,8-pentazabicyclo[4.3.0]nona-2,7,9-triene-9-carboxamide; 8-Carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one; NSC 362856

CAS Number: 85622-93-1
Empirical Formula (Hill Notation): C₆H₆N₆O₂
Molecular Weight: 194.15
MDL Number: MFCD00866492
Linear Formula: C₆H₆N₆O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-76899-10MG	10 mg	$221.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 76899-10MG

Properties
Descriptions
Safety Info.
Basic Data

application(s)	forensics and toxicology pharmaceutical (small molecule) veterinary
assay	≥99.0% (HPLC)
format	neat
grade	analytical standard
ign. residue	≤0.2%
InChI	1S/C6H6N6O2/c1-11-6(14)12-2-8-3(4(7)13)5(12)9-10-11/h2H,1H3,(H2,7,13)
InChI key	BPEGJWRSRHCHSN-UHFFFAOYSA-N
loss	≤0.5% loss on drying
product line	VETRANAL^®
Quality Level	100
shelf life	limited shelf life, expiry date on the label
SMILES string	CN1N=Nc2c(ncn2C1=O)C(N)=O
storage temp.	2-8°C
technique(s)	gas chromatography (GC): suitable
	HPLC: suitable

Application:	Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Application:	TMZ may be used as a reference standard for the analysis of temozolomide in serum and brain tumor samples by micellar electrokinetic capillary chromatography (MEKC), in aqueous solutions by liquid chromatography-electrospray-tandem mass spectrometry (LC-ESI-MS/MS), in active pharmaceutical ingredients (APIs) by high performance liquid chromatography (HPLC) with MS/MS and in pharmaceutical dosage form by HPLC equipped with photodiode array (PDA) detector.
General description:	Temozolomide (TMZ) is an alkylating agent of the imidazotetrazine derivatives that shows broad-spectrum antitumor activity against murine tumors.
Legal Information:	VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Symbol	GHS07,GHS08
Signal word	Danger
Hazard statements	H302 - H315 - H319 - H335 - H340 - H350 - H360FD
Precautionary statements	P201 - P202 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
Hazard Codes	T
Risk Statements	45-46-60-61-22-36/37/38
Safety Statements	53-26-36/37-45
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3

Purity	≥99.0% (HPLC)
Storage Temp.	2-8°C
UNSPSC	41116107

To Order From a Quote