Tetrahydrofuran
SIAL/78445 - analytical standard
Synonym: Butylene oxide; Oxolane; Tetramethylene oxide
CAS Number: 109-99-9
Empirical Formula (Hill Notation): C4H8O
Molecular Weight: 72.11
EC Number: 203-726-8
MDL Number: MFCD00005356
Linear Formula: C4H8O
Product Type: Chemical
| application(s) | cleaning products cosmetics environmental food and beverages personal care |
| assay | ≥99.9% (GC) |
| autoignition temp. | 610 °F |
| bp | 65-67 °C (lit.) |
| contains | ~0.025% 2,6-di-tert.-butyl-4-methylphenol as stabilizer |
| density | 0.889 g/mL at 25 °C (lit.) |
| expl. lim. | 1.8-11.8 % |
| format | neat |
| grade | analytical standard |
| InChI | 1S/C4H8O/c1-2-4-5-3-1/h1- |
| InChI key | WYURNTSHIVDZCO-UHFFFAOYSA |
| mp | −108 °C (lit.) |
| Quality Level | 100  |
| refractive index | n |
| shelf life | limited shelf life, expiry date on the label |
| SMILES string | C1CCOC1 |
| solubility | H2O: soluble |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable | |
| vapor density | 2.5 (vs air) |
| vapor pressure | 114 mmHg ( 15 °C) |
| 143 mmHg ( 20 °C) |
| Application: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
| Application: | Tetrahydrofuran may be used as an extraction solvent for the determination of pesticide residues in olive oil and phthalates in toys and child care articles by chromatography techniques. |
| Application: | Tetrahydrofuran may find application as a solvent in the synthesis of (S)-2-(1-pyrrolidinylmethyl |
| General description: | Tetrahydrofuran (THF) is a saturated cyclic ether. Its potential use as a biofuel for internal combustion engines is investigated. |
| General description: | Tetrahydrofuran is an important basic chemical compound, which belongs to the category of 5-membered heterocycles. |
| General description: | This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. |
| Symbol |    GHS02,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H225 - H302 - H319 - H335 - H336 - H351 |
| Precautionary statements | P201 - P202 - P210 - P301 + P312 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | F,Xn |
| Risk Statements | 11-19-36/37-40 |
| Safety Statements | 13-16-29-33-36-37-46 |
| RIDADR | UN 2056 3 / PGII |
| WGK Germany | WGK 1 |
| Flash Point(F) | -6.2 °F - closed cup |
| Flash Point(C) | -21.2 °C - closed cup |
| Supplemental Hazard Statements | EUH018 - EUH019 |
| Purity | ≥99.9% (GC) |
| bp | 65-67 °C (lit.) |
| mp | −108 °C (lit.) |
| Density | 0.889 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12191501 |