Tetrahydrofuran
SIAL/78445 - analytical standard
Synonym: Butylene oxide; Oxolane; Tetramethylene oxide
CAS Number: 109-99-9
Empirical Formula (Hill Notation): C4H8O
Molecular Weight: 72.11
EC Number: 203-726-8
MDL Number: MFCD00005356
Linear Formula: C4H8O
Product Type: Chemical
application(s) | cleaning products cosmetics environmental food and beverages personal care |
assay | ≥99.9% (GC) |
autoignition temp. | 610 °F |
bp | 65-67 °C (lit.) |
contains | ~0.025% 2,6-di-tert.-butyl-4-methylphenol as stabilizer |
density | 0.889 g/mL at 25 °C (lit.) |
expl. lim. | 1.8-11.8 % |
format | neat |
grade | analytical standard |
InChI | 1S/C4H8O/c1-2-4-5-3-1/h1- |
InChI key | WYURNTSHIVDZCO-UHFFFAOYSA |
mp | −108 °C (lit.) |
Quality Level | 100 ![]() |
refractive index | n |
shelf life | limited shelf life, expiry date on the label |
SMILES string | C1CCOC1 |
solubility | H2O: soluble |
technique(s) | gas chromatography (GC): suitable |
HPLC: suitable | |
vapor density | 2.5 (vs air) |
vapor pressure | 114 mmHg ( 15 °C) |
143 mmHg ( 20 °C) |
Application: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
Application: | Tetrahydrofuran may be used as an extraction solvent for the determination of pesticide residues in olive oil and phthalates in toys and child care articles by chromatography techniques. |
Application: | Tetrahydrofuran may find application as a solvent in the synthesis of (S)-2-(1-pyrrolidinylmethyl |
General description: | Tetrahydrofuran (THF) is a saturated cyclic ether. Its potential use as a biofuel for internal combustion engines is investigated. |
General description: | Tetrahydrofuran is an important basic chemical compound, which belongs to the category of 5-membered heterocycles. |
General description: | This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. |
Symbol | ![]() ![]() ![]() |
Signal word | Danger |
Hazard statements | H225 - H302 - H319 - H335 - H336 - H351 |
Precautionary statements | P201 - P202 - P210 - P301 + P312 - P305 + P351 + P338 - P308 + P313 |
Hazard Codes | F,Xn |
Risk Statements | 11-19-36/37-40 |
Safety Statements | 13-16-29-33-36-37-46 |
RIDADR | UN 2056 3 / PGII |
WGK Germany | WGK 1 |
Flash Point(F) | -6.2 °F - closed cup |
Flash Point(C) | -21.2 °C - closed cup |
Supplemental Hazard Statements | EUH018 - EUH019 |
Purity | ≥99.9% (GC) |
bp | 65-67 °C (lit.) |
mp | −108 °C (lit.) |
Density | 0.889 g/mL at 25 °C (lit.) |
Refractive Index | n |
UNSPSC | 12191501 |