Levetiracetam
SIAL/78645 - analytical standard
Synonym: (αS)-α-Ethyl-2-oxo-1-pyrrolidineacetamide; 2(S)
CAS Number: 102767-28-2
Empirical Formula (Hill Notation): C8H14N2O2
Molecular Weight: 170.21
MDL Number: MFCD03265610
Linear Formula: C8H14N2O2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 78645-10MG
| application(s) | forensics and toxicology veterinary |
| assay | ≥98.0% (HPLC) |
| format | neat |
| grade | analytical standard |
| InChI | 1S/C8H14N2O2/c1-2-6(8(9)1 |
| InChI key | HPHUVLMMVZITSG-LURJTMIESA |
| optical activity | [α]/D -90±5°, c = 1 in acetone |
| Quality Level | 100  |
| shelf life | limited shelf life, expiry date on the label |
| SMILES string | CC[C@H](N1CCCC1=O)C(N)=O |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Application: | Levetiracetam may be used as a reference standard in the determination of levetiracetam in biological fluid samples using high-performance liquid chromatography coupled with electrospray tandem mass spectrometry (HPLC-ESI-MS/MS). |
| Application: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
| Biochem/physiol Actions: | Levetiracetam is a pyrrolidine with antiepileptic activity. Stereoselective binding of levetiracetam was confined to synaptic plasma membranes in the central nervous system with no binding occurring in peripheral tissue. Levetiracetam inhibits burst firing without affecting normal neuronal excitability, which suggests that it may selectively prevent hyper-synchronization of epileptiform burst firing and propagation of seizure activity. |
| General description: | Levetiracetam is an orally active antiepileptic drug, having a high therapeutic index and potential antiepileptogenic and anticonvulsant effects. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 - H319 |
| Precautionary statements | P301 + P312 + P330 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-36 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98.0% (HPLC) |
| UNSPSC | 41116107 |