ProClin™ 950
SIAL/799130 - pkg of 110 kg
Synonym: 2-
Product Type: Chemical
ProClin 950 attacks the central metabolic cycle of the cell, the Krebs cycle, at two specific enzymatic sites: succinate dehydrogenase and NADH dehydrogenase. Other inhibited enzymes include pyruvate dehydrogenase, which is vital for oxidation of pyruvate to acetyl-CoA; as well as lactate dehydrogenase and alcohol dehydrogenase, which detoxify waste byproducts synthesized during fermentation. With cellular metabolism debilitated, microorganisms rapidly lose their ability to produce ATP and carry on vital functions, such as transcription, translation and damage repair. All bacteria and fungi possess at least some parts of the Krebs cycle, thus ProClin 950 represents a highly efficient broad spectrum biocide.
12 Principles of Green Chemistry: Principle 4—Designing Safer Chemicals
Chemical products should be designed to affect their desired function while minimizing their toxicity.
Chemical products should be designed to affect their desired function while minimizing their toxicity.
| composition | MIT, 9.5% |
| description | biocide for IVD use |
| form | liquid |
| greener alternative category | Aligned  |
| greener alternative product characteristics | Designing Safer Chemicals Learn more about the Principles of Green Chemistry . |
| matrix | Water |
| operating pH range | 2-12 |
| packaging | pkg of 110 kg |
| Quality Level | 100 |
| Application: | ProClin biocides are immediately microstatic upon contact with microbial organisms as a result of their ability to quickly penetrate cell membranes and inhibit specific enzymes crucial to cellular respiration. Multiple specific sites of ProClin toxicity prevent microorganisms from developing high levels of resistance, making ProClin highly efficient even over extended storage periods of your IVD components. |
| General description: | We are committed to bringing you greener alternative products, which adhere to one or more of The 12 Principles of Green Chemistry. ProClin™ 950 is a most effective biocide, which is an eco-friendly alternative to NaN3. It reduces health hazard, toxicology problems or disposal issues and thus this product aligns with "Design for Safer chemicals". Click here for more information. |
| Legal Information: | ProClin is a trademark of The Dow Chemical Company or an affiliated company of Dow |
| Linkage: | For additional technical details on ProClin, including key features and mechanism of action, please visit www.sigmaaldrich.com/proc. |
| Packaging: | 110 kg in poly drum |
| Symbol |    GHS05,GHS07,GHS09 |
| Signal word | Danger |
| Hazard statements | H314 - H317 - H332 - H410 |
| Precautionary statements | P261 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| RIDADR | UN3265 - class 8 - PG 2 - EHS - Corrosive liquid, acidic, organi |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Supplemental Hazard Statements | EUH071 |
| UNSPSC | 12352200 |