Methoxyamine hydrochloride
SIAL/89803 - for GC derivatization, LiChropur™, 97.5-102.5% (AT)
Synonym: O-Methylhydroxylamine hydrochloride; Methoxylamine hydrochloride
CAS Number: 593-56-6
Empirical Formula (Hill Notation): CH5NO · HCl
Molecular Weight: 83.52
MDL Number: MFCD00012951
Linear Formula: CH3ONH2 · HCl
Product Type: Chemical
| assay | 97.5-102.5% (AT) |
| form | crystals |
| grade | for GC derivatization |
| InChI | 1S/CH5NO.ClH/c1-3-2;/h2H2 |
| InChI key | XNXVOSBNFZWHBV-UHFFFAOYSA |
| mp | 151-154 °C (lit.) |
| quality | LiChropur™ |
| Quality Level | 100  |
| reaction suitability | reagent type: derivatization reagent reaction type: Acylations |
| SMILES string | Cl.CON |
| technique(s) | gas chromatography (GC): suitable |
| Application: | Methoxyamine hydrochloride can be used as: • A reagent for the preparation of O-methyl oximes. • A reagent used to make O-methyl oximes from aldehydes or ketones. • An alkylation reagent. • It may be used as a derivatization agent to improve the sensitivity of opioids, steroids and ionic metabolites in biological samples and non-volatile flavor compounds in "Angeleno" plum fruit prior to the determination of analytes using gas chromatography-mass spectrometry (GC-MS) technique. |
| General description: | Methoxyamine hydrochloride is a commonly used reagent for the generation of oxime derivatives of aldehyde- or ketone-group containing compounds. It is typically employed as an oximation reagent prior to silylation derivatizations. |
| Legal Information: | LiChropur is a trademark of Merck KGaA, Darmstadt, Germany |
| Recommended products: | Discover LiChropur™ reagents ideal for HPLC or LC-MS analysis |
| Symbol |     GHS05,GHS07,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H290 - H302 + H312 - H315 - H317 - H319 - H351 - H372 - H410 |
| Precautionary statements | P201 - P273 - P280 - P301 + P312 + P330 - P302 + P352 + P312 - P308 + P313 |
| RIDADR | UN3261 - class 8 - PG 2 - EHS - Corrosive solid, acidic, organic |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 97.5-102.5% (AT) |
| mp | 151-154 °C (lit.) |
| UNSPSC | 41116105 |