PC biotin-PEG3-NHS ester
SIAL/901767
Synonym: PC biotin-NHS ester
CAS Number: 2353409-93-3
Empirical Formula (Hill Notation): C36H52N6O15S
Molecular Weight: 840.89
Linear Formula: C36H52N6O15S
Product Type: Chemical
form | solid |
mp | 170 °C |
reaction suitability | reaction type: click chemistry |
reagent type: cross-linking reagent | |
storage temp. | −20°C |
Application: | PC biotin-NHS ester is a unique amine-reactive, photocleavable biotin reagent that allows for reagent-free release of the captured biomolecules from streptavidin. This reagent contains a biotin moiety linked to the amine reactive N-hydroxysuccinimidyl (NHS) mixed carbonate through a spacer arm containing a photocleavable moiety. The NHS portion of this compound reacts specifically with primary amine groups on the target molecule(s) to form a carbamate linkage. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2). |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
mp | 170 °C |
Storage Temp. | −20°C |
UNSPSC | 51171641 |