Tetrazine-NHS ester
SIAL/901989
Empirical Formula (Hill Notation): C14H11N5O4
Molecular Weight: 313.27
MDL Number: MFCD29052194
Linear Formula: C14H11N5O4
Product Type: Chemical
| availability | available only in USA |
| form | powder |
| mp | 171-177 °C |
| storage temp. | −20°C |
| Application: | Tetrazine-NHS ester demonstrates exceptionally fast cycloaddition kinetics with trans-cyclooctene (TCO) as the dienophile (up to 30,000 M-1 s-1). These have been the fastest kinetics reported for a bioorthogonal reaction. The chemical stability of tetrazines is substantially lower compared to methyltetrazines, thus requiring more careful selection of reagents and conditions for chemical transformation. However, tetrazine chemistry is still in an acceptable range for many applications. |
| Symbol |  GHS02 |
| Signal word | Danger |
| Hazard statements | H242 |
| Precautionary statements | P210 - P234 - P235 - P240 - P370 + P378 - P403 |
| RIDADR | transport forbidden |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 171-177 °C |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |