TyrannoPhos
SIAL/902284
Synonym: Cyclopentylbis(3,5-
CAS Number: 2097604-70-9
Empirical Formula (Hill Notation): C33H51P
Molecular Weight: 478.73
Linear Formula: C33H51P
Product Type: Chemical
form | powder or crystals |
functional group | phosphine |
reaction suitability | reaction type: Buchwald-Hartwig Cross Coupling Reaction |
reaction type: Heck Reaction | |
reaction type: Hiyama Coupling | |
reaction type: Negishi Coupling | |
reaction type: Sonogashira Coupling | |
reaction type: Stille Coupling | |
reaction type: Suzuki-Miyaura Coupling | |
reagent type: ligand | |
SMILES string | CC(C1=CC(P(C2=CC(C(C)(C)C |
Application: | This new aryl alkylphosphine ligand developed in Abby′s Doyle′s lab has been tailored specifically for nickel catalysis as demonstrated in the Suzuki coupling of acetals with boronic acids to generate benzylic ethers, reactions that pose challenges in Ni catalysis when using phosphine ligands developed for Pd-catalysed couplings. |
Other Notes: | Parameterization of phosphine ligands demonstrates enhacement of nickel catalysis via remote steric effects ![]() ![]() |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
UNSPSC | 12352200 |