Synonym: 1,2,3-Triacetoxypropane; 1,2,3-Triacetylglycerol; Glycerol triacetate; Triacetin
CAS Number: 102-76-1
Empirical Formula (Hill Notation): C9H14O6
Molecular Weight: 218.20
EC Number: 203-051-9
MDL Number: MFCD00008716
Linear Formula: (CH3COOCH2)2CHOCOCH3
Product Type: Chemical
| assay |
≥99.0% (GC) |
| bp |
258-260 °C (lit.) |
| density |
1.158 g/mL at 20 °C |
| form |
liquid |
| InChI |
1S/C9H14O6/c1-6(10)13-4-9(15-8(3)12)5-14-7(2)11/h9H,4-5H2,1-3H3 |
| InChI key |
URAYPUMNDPQOKB-UHFFFAOYSA-N |
| lipid type |
saturated FAs |
| Quality Level |
200  |
| refractive index |
n20/D 1.431 |
| SMILES string |
CC(=O)OCC(COC(C)=O)OC(C)=O |
| Application: |
- Epigenetic priming targets tumor heterogeneity to shift transcriptomic phenotype of pancreatic ductal adenocarcinoma towards a Vitamin D susceptible state.: This groundbreaking study utilizes glyceryl triacetate as part of an epigenetic priming strategy to sensitize pancreatic ductal adenocarcinoma to Vitamin D, marking a significant advancement in cancer treatment modalities (He et al., 2024
 ).
- Glyceryl triacetate promotes blood-brain barrier recovery after ischemic stroke through lipogenesis-mediated IL-33 in mice.: Research demonstrates glyceryl triacetate′s effectiveness in enhancing blood-brain barrier repair post-ischemic stroke via lipogenesis pathways, offering insights into novel stroke recovery treatments (Wei et al., 2023 ).
- Development of A Nanostructured Lipid Carrier-Based Drug Delivery Strategy for Apigenin: Experimental Design Based on CCD-RSM and Evaluation against NSCLC In Vitro.: This study details the formulation of a nanostructured lipid carrier incorporating glyceryl triacetate, optimized for delivering apigenin to combat non-small cell lung cancer, emphasizing the potential of glyceryl triacetate in targeted therapy applications (Wang et al., 2023 ).
- Are New Phthalate Ester Substitutes Safer than Traditional DBP and DiBP Comparative Endocrine-Disrupting Analyses on Zebrafish Using In Vivo, Transcriptome, and In Silico Approaches.: Investigating glyceryl triacetate as a safer alternative to traditional phthalate esters, this study explores its lower endocrine-disrupting effects, contributing to safer industrial and pharmaceutical applications (Tan et al., 2023 ).
- Glyceryl triacetate feeding in mice increases plasma acetate levels but has no anticonvulsant effects in acute electrical seizure models.: This research evaluates the biochemical impact of glyceryl triacetate on plasma acetate levels, providing valuable data on its metabolic effects despite a lack of anticonvulsant properties in specific seizure models (Xu et al., 2022 ).
|
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
298.4 °F - closed cup |
| Flash Point(C) |
148 °C - closed cup |
| Purity |
≥99.0% (GC) |
| bp |
258-260 °C (lit.) |
| Density |
1.158 g/mL at 20 °C |
| Refractive Index |
n20/D 1.431 |
| UNSPSC |
12352211 |
