Polyvinylpyrrolidone

SIAL/90268 - K 25, tested according to Ph. Eur.

Synonym: PVP; Polyvidone; Povidone

CAS Number: 9003-39-8
MDL Number: MFCD00149016
Linear Formula: (C₆H₉NO)_n
Product Type: Chemical

agency	tested according to Ph. Eur.
form	powder
InChI	1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2
InChI key	WHNWPMSKXPGLAX-UHFFFAOYSA-N
Quality Level	100
SMILES string	C=CN1CCCC1=O

Application:

Colyophilized Sugar-Polymer Dispersions for Enhanced Processing and Storage Stability.: This study explores the use of polyvinylpyrrolidone in colyophilized sugar-polymer dispersions to improve the processing and storage stability of pharmaceuticals. The research demonstrates how combining sugars with polyvinylpyrrolidone enhances the physical stability and performance of the resulting dispersions, which is crucial for maintaining drug efficacy during storage and handling (Giannachi et al., 2024 ).

Fabrication and evaluation of stable amorphous polymer-drug composite particles via a nozzle-free ultrasonic nebulizer.: This article discusses the development of amorphous polymer-drug composite particles using polyvinylpyrrolidone and a nozzle-free ultrasonic nebulizer. The findings indicate that polyvinylpyrrolidone helps in stabilizing the amorphous form of the drug, which can enhance its solubility and bioavailability (Lee et al., 2024 ).

Polymer-Assisted Coprecipitation Synthesized Zinc Oxide Nanoparticles and Their Uses for Gre en Chemical Synthesis via Photocatalytic Glucose Conversions.: This study presents a novel method of using polyvinylpyrrolidone in the synthesis of zinc oxide nanoparticles. The research shows that these nanoparticles can be used in green chemical processes, such as the photocatalytic conversion of glucose, showcasing the versatility of polyvinylpyrrolidone in catalysis and material science (Kaewsaenee et al., 2023 ).

Development and evaluation of the in vitro schistosomicidal activity of solid dispersions based on 2-(-5-bromo-1-H-indole-3-yl-methylene)-N-(naphthalene-1-ylhydrazine-carbothiamide).: This article explores the use of polyvinylpyrrolidone in formulating solid dispersions for antiparasitic treatments. The findings demonstrate that polyvinylpyrrolidone can enhance the solubility and efficacy of the active pharmaceutical ingredient against parasitic infections (de Luna Rocha et al., 2024 ).

Other Notes:

Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

UNSPSC

12352005