Bradykinin acetate salt
SIAL/90834 - analytical standard
CAS Number: 6846-03-3
Empirical Formula (Hill Notation): C50H73N15O11 · xC2H4O2
Molecular Weight: 1060.21 (free base basis)
EC Number: 227-781-2
Linear Formula: C50H73N15O11 · xC2H4O2
Product Type: Chemical
analyte chemical class(es) | peptides |
application(s) | food and beverages |
assay | ≥98.0% (HPLC) |
color | white |
format | neat |
grade | analytical standard |
impurities | ≤10 wt. % water |
InChI | 1S/C50H73N15O11/c51-32(16 |
InChI key | QXZGBUJJYSLZLT-FDISYFBBSA |
Quality Level | 100 |
shelf life | limited shelf life, expiry date on the label |
storage temp. | 2-8°C |
technique(s) | HPLC: suitable |
Amino Acid Sequence: | Arg-Pro-Pro-Gly-Phe-Ser-P |
Application: | Bradykinin acetate salt may be used as a precursor for the preparation of bradykinin (BK) prior to its determination from acidic aqueous solutions by electromembrane extraction (EME) followed by analysis using high performance liquid chromatography (HPLC) with ultraviolet (UV) detector. |
Application: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
Biochem/physiol Actions: | Bradykinin is a pro-inflammatory peptide that acts through G-protein-coupled receptors. It activates sphingolipid metabolism. Fibroblasts treated with bradykinin produce a rapid and important increase in ceramide which is followed by a transient rise in sphingosine content. The peptide also increases ceramide cellular content by rapidly mobilizing neutral glycolipids. Bradykinin plays an important role in the regulation of fluid and electrolyte balance, smooth muscle contraction, vasodilation and capillary permeability. The bradykinin potentiators, which possess no bradykinin activity themselves, enhance the activity of bradykinin. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98.0% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 85151701 |