TIPS-5-Ethynyl-dU-CEP
SIAL/909580
Synonym: TIPS-5-EdU CEP; TIPS-5-Ethynyl dU CEP; TIPS-5-Ethynyl dU phosphoramidite
Empirical Formula (Hill Notation): C50H67N4O8PSi
Molecular Weight: 911.15
Linear Formula: C50H67N4O8PSi
Product Type: Chemical
form | powder |
mp | >300 °C |
reaction suitability | reaction type: click chemistry |
storage temp. | −20°C |
Application: | This functional phosphoramidite is used to introduce click handles universally (5′ internal and 3′ end) into oligonucleotides under standard conditions for solid phase synthesis. Afterwards the oligonucleotide (RNA, PNA, DNA) can be efficiently conjugated using a copper catalyzed click reaction to azide functionalized moieties such as fluorescent dye azides and azido amino acids. In contrast to 5-Ethynyl dU CEP, TIPS-5-EdU CEP allows side product free synthesis of highly modified oligonucleotides (>10 modifications). |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
mp | >300 °C |
Storage Temp. | −20°C |