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4-Azido-L-homoalanine hydrochloride

SIAL/909815 - ≥98%

Synonym: (S)-2-Amino-4-azidobutanoic acid hydrochloride; 4-Azido-L-homoalanine HCl; 4-Azido-L-homoalanine hydrochloride; H-L-Aha-OH*HCl

CAS Number: 942518-29-8
Empirical Formula (Hill Notation): C4H8N4O2 · HCl
Molecular Weight: 180.59
Linear Formula: C4H8N4O2 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-909815-100MG 100 mg
 $327.00
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assay ≥98%
availability available only in USA
form powder
reaction suitability reaction type: solution phase peptide synthesis
storage temp. 2-8°C
Application: The in vivo incorporation of clickable unnatural amino acids such as 4-Azido-L-homoalanine with unique reactivity at a defined postition is used for functionalization of proteins. The azide functionalities in the protein can then be modified with almost any alkyne bearing molecule by Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC). Copper-free alternatives with strained internal alkynes are also available (SPAAC). Some examples enabled with this technique are protein PEGylation, masking with sugars, and the attachment to antibodies.
Purity ≥98%
Storage Temp. 2-8°C
UNSPSC 12352200

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