γ-Valerolactone
SIAL/918660 - BioRenewable, ≥99%, ReagentPlus®
Synonym: γ-Methyl-γ-butyrolactone; γ-Methyl-γ-butyrolactone; 4,5-
CAS Number: 108-29-2
Empirical Formula (Hill Notation): C5H8O2
Molecular Weight: 100.12
MDL Number: MFCD00005400
Linear Formula: C5H8O2
Product Type: Chemical
12 Principles of Green Chemistry: Principle 5—Safer Solvents and Auxiliaries. This product utilizes reduced volumes of auxiliary substances that are less hazardous.
12 Principles of Green Chemistry: Principle 7—A raw material or feedstock should be renewable rather than depleting whenever technically and economically practicable.
12 Principles of Green Chemistry: Principle 10—Chemical products should be designed so that at the end of their function they break down into innocuous degradation products and do not persist in the environment.
| assay | ≥99% |
| bp | 207-208 °C (lit.) |
| 82-85 °C/10 mmHg (lit.) | |
| density | 1.05 g/mL at 25 °C (lit.) |
| form | liquid |
| greener alternative category | Aligned  |
| greener alternative product characteristics | Safer Solvents and Auxiliaries Use of Renewable Feedstocks Design for Degradation Learn more about the Principles of Green Chemistry . |
| InChI | 1S/C5H8O2/c1-4-2-3-5(6)7- |
| InChI key | GAEKPEKOJKCEMS-UHFFFAOYSA |
| mp | −31 °C (lit.) |
| product line | ReagentPlus® |
| Quality Level | 100 |
| refractive index | n |
| SMILES string | CC1CCC(=O)O1 |
| vapor density | 3.45 (vs air) |
| Application: | Cross-coupling reactions• HATU Amide Coupling • Suzuki-Miyaura coupling reaction • Sonogashira coupling reaction ATRP polymerization• Replaceme |
| Features and Benefits: | • Made from Renewable Resource - rice • Biodegradable • Non-toxic • Low vapor pressure |
| General description: | We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. γ-Valerolactone (GVL) is a dipolar aprotic, bio-based, fully degradable, non-toxic green solvent and has been aligned with "Safer Solvent and Auxiliaries", "Use of Renewable Feedstocks" and "Design for Degradation". Click here  for more information. γ-Valerolactone is a sustainable alternative to traditional solvents such as NMP and DMF. We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. γ-Valerolactone (GVL) is a bio-based, fully degradable, non-toxic green solvent and has been aligned with "Safer Solvent and Auxiliaries", "Use of Renewable Feedstocks" and "Design for Degradation". Click here for more information. |
| Legal Information: | ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC |
| Other Notes: | To see other BioRenewable or Greener Solvents |
| WGK Germany | WGK 2 |
| Flash Point(F) | 204.8 °F - closed cup |
| Flash Point(C) | 96 °C - closed cup |
| Purity | ≥99% |
| bp | 207-208 °C (lit.); 82-85 °C/10 mmHg (lit.) |
| mp | −31 °C (lit.) |
| Density | 1.05 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352300 |