Cyrene™ γ-Valerolactone Blend
SIAL/920207 - BioRenewable
Synonym: γ-Valerolactone Cyrene™ solution; γ-Valerolactone solution; Cyrene solution; Cyrene™ γ-valerolactone solution
Empirical Formula (Hill Notation): C6H8O3
Molecular Weight: 128.13
Linear Formula: C6H8O3
Product Type: Chemical
density | 1.141 g/mL |
form | liquid |
greener alternative category | Aligned ![]() |
greener alternative product characteristics | Safer Solvents and Auxiliaries Use of Renewable Feedstocks Learn more about the Principles of Green Chemistry ![]() |
renewable carbon content | 100% |
Application: | This cosolvent solution has been shown to have similar reaction yields to NMP and DMF for many cross-coupling reactions, such as: • HATU Amide Coupling - Replacement for DMF in amide and dipeptide coupling reactions • Suzuki-Miyaura coupling reaction • Sonogashira coupling reaction |
Features and Benefits: | • Independently certified as 100% renewable carbon. • Closer physical properties of NMP and DMF while maintaining high reaction yields. • Sustainably produced and environmentally less hazardous than more traditional petroleum aprotic solvents • Both Cyrene • It has a lower viscosity than neat Cyrene |
General description: | Cyrene™ γ-Valerolactone Blend is specially formulated for use in automated processes and applications where lower viscosity is required, making it easier to handle while maintaining high yields. This Cyrene™ blend is an alternative for NMP and DMF in many cross-coupling reactions. Neither Cyrene™ nor γ-Valerolactone have any genotoxic or mutagenic concerns associated with their use, making them much safer alternatives to traditional aprotic solvents. This new blend is part of our Biorenewable ![]() |
Legal Information: | CYRENE is a trademark of Circa Group Pvt Ltd |
Other Notes: | To see other BioRenewable or Greener Solvents ![]() |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H319 |
Precautionary statements | P264 - P280 - P305 + P351 + P338 - P337 + P313 |
WGK Germany | WGK 2 |
Density | 1.141 g/mL |