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O-Acetyl-L-carnitine hydrochloride

SIAL/92107 - analytical standard

Synonym: (R)-3-Acetoxy-4-(trimethylammonio)butyrate hydrochloride; ALC; ALCAR; R-(−)-2-Acetyloxy-3-carboxy-N,N,N-trimethyl-1-propanaminium chloride

CAS Number: 5080-50-2
Empirical Formula (Hill Notation): C9H17NO4 · HCl
Molecular Weight: 239.70
MDL Number: MFCD00082230
Linear Formula: C9H17NO4 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-92107-10MG 10 mg
 $0.00
1/EA
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45-92107-50MG 50 mg
 $211.00
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application(s) clinical testing
assay ≥96.0% (HPLC)
  96.0-104.0% (AT)
color white to off-white
form powder or crystals
format neat
grade analytical standard
InChI 1S/C9H17NO4.ClH/c1-7(11)14-8(5-9(12)13)6-10(2,3)4;/h8H,5-6H2,1-4H3;1H/t8-;/m1./s1
InChI key JATPLOXBFFRHDN-DDWIOCJRSA-N
optical activity [α]/D -27.0±2.0°, c = 1 in H2O
Quality Level 100 
shelf life limited shelf life, expiry date on the label
SMILES string [Cl-].CC(=O)O[C@H](CC(O)=O)C[N+](C)(C)C
storage temp. 2-8°C
Application: O-Acetyl-L-carnitine hydrochloride may be used as a precursor for the preparation of O-Acetyl-L-carnitine, which in turn may be used as an analytical reference standard for the determination of the analyte in biological samples by hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS) technique.
Biochem/physiol Actions: Endogenous mitochondrial metabolite that transports acetyl groups across the mitochondrial membrane. Exogenous acetylcarnitine enhances mitochondrial function in aged rats. As an acetate donor to coenzyme A, it increases the central and peripheral acetylcholine synthesis and function. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors.
General description: Acetyl carnitine is one of the major acylcarnitines produced during the transport of long-chain fatty acids in the body.
Purity ≥96.0% (HPLC); 96.0-104.0% (AT)
Storage Temp. 2-8°C
UNSPSC 41116107

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