Palladium(II) Acetate ChemBeads
SIAL/924377
CAS Number: 3375-31-3
MDL Number: MFCD00012453
Linear Formula: Pd(OCOCH3)2
Product Type: Chemical
| composition | ~ 4 wt.% loading of catalyst |
| form | solid |
| Quality Level | 100  |
| reaction suitability | core: palladium reaction type: Buchwald-Hartwig Cross Coupling Reaction |
| core: palladium reaction type: Heck Reaction |
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| core: palladium reaction type: Hiyama Coupling |
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| core: palladium reaction type: Negishi Coupling |
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| core: palladium reaction type: Sonogashira Coupling |
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| core: palladium reaction type: Stille Coupling |
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| core: palladium reaction type: Suzuki-Miyaura Coupling |
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| reagent type: catalyst |
| Application: | Application Guide for Palladium Catalyzed Cross-Coupling Reactions Catalyst for an intramolecular coupling of aryl bromides with alcohols giving 1,3-oxazepines. Preparation of cyclic ureas via palladium-catalyzed intramolecular cyclization. ChemBeads are chemical coated glass beads. ChemBeads offer improved flowability and chemical uniformity perfect for automated solid dispensing and high-throughput experimentation. The method of creating ChemBeads uses no other chemicals or surfactants allowing the user to accurately dispense sub-milligram amounts of chemical. |
| General description: | Palladium(II) acetate is a homogenous oxidation catalyst. It participates in the activation of alkenic and aromatic compounds towards oxidative inter- and intramolecular nucleophilic reactions. Crystals of palladium(II) acetate have a trimeric structure, having symmetry D3h. Each of the palladium atoms in the crystals are joined to the other two by double acetate bridges. Microencapsulation of palladium(II) acetate in polyurea affords polyurea-encapsulated palladium(II) acetate. It is a versatile heterogeneous catalyst for various phosphine-free cross-coupling reactions. It participates as catalyst in the Heck coupling reaction of pthalides with different alkenes. |
| Other Notes: | High-Throughput Reaction Screening with Nanomoles of Solid Reagents Coated on Glass Beads  Versatile Methods to Dispense Sub-Milligram Quantities of Solids using Chemical Coated Beads for High-Throughput Experimentation ChemBead Enabled High-Throughput Cross-Electrophile Coupling Reveals a New Complementary Ligand |
| Symbol |    GHS05,GHS07,GHS09 |
| Signal word | Danger |
| Hazard statements | H317 - H318 - H410 |
| Precautionary statements | P261 - P272 - P273 - P280 - P302 + P352 - P305 + P351 + P338 |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |