Disodium (2RS)-2-hydroxyadipate
SIAL/92826 - analytical standard
Synonym: α-Hydroxyadipic acid disodium salt; (2RS)-2-Hydroxyadipic acid disodium salt; 2-Hydroxyhexanedioic acid disodium salt
Empirical Formula (Hill Notation): C6H8Na2O5
Molecular Weight: 206.10
Linear Formula: C6H8Na2O5
Product Type: Chemical
| application(s) | clinical testing |
| assay | ≥94.0% (GC) |
| format | neat |
| grade | analytical standard |
| Quality Level | 100  |
| shelf life | limited shelf life, expiry date on the label |
| Analysis Note: | may contain ethanol |
| Biochem/physiol Actions: | 2-Hydroxyadipic acid is a hydroxy-dicarboxylic acid formed by the reduction of 2-ketoadipic acid. Deficiency of 2-ketoadipic dehydrogenase causes 2-ketoadipic academia, a condition characterized by accumulation and excretion of 2-hydroxyadipic acid. A method involving derivatization and combined gas chromatography-mass spectrometry has been recently developed to separate the enantiomers of 3-hydroxyadipic acid. It has been shown that 3-hydroxyadipic acid excreted in urine consists of at least 95% of the L-enantiomer. This finding supports the hypothesis that dicarboxylic acids are degraded by ordinary beta-oxidation, and indicates that adipic acid may be converted into succinic acid. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥94.0% (GC) |
| UNSPSC | 12352200 |