Trizma® base
SIAL/93440 - reference material for titrimetry, certified by BAM, >99.5%
Synonym: 2-
CAS Number: 77-86-1
Empirical Formula (Hill Notation): C4H11NO3
Molecular Weight: 121.14
EC Number: 201-064-4
MDL Number: MFCD00004679
Linear Formula: NH2C(CH2OH)3
Product Type: Chemical
| assay | >99.5% |
| bp | 219-220 °C/10 mmHg (lit.) |
| description | aminopeptidase substrate |
| format | neat |
| grade | reference material |
| InChI | 1S/C4H11NO3/c5-4(1-6,2-7) |
| InChI key | LENZDBCJOHFCAS-UHFFFAOYSA |
| mp | 167-172 °C (lit.) |
| pH | 10.5-12 |
| pKa (25 °C) | 8.1 |
| quality | certified by BAM |
| Quality Level | 100 ![]() |
| SMILES string | NC(CO)(CO)CO |
| solubility | water: soluble (678 g/l at 20 °C) |
| technique(s) | titration: suitable |
| useful pH range | 7-9 |
| Analysis Note: | Exact concentration, expiry date, traceability and detailed information on certification can be found on the certificate and certification report, included in each package. Content and expiry date on label. |
| Application: | It finds its use as a reference material for the standardization of volumetric solutions in acidimetric titrations. |
| Features and Benefits: | • Available as a solid in a secure glass bottle to ensure its stability for the entire shelf life until opened. • High-purity material traceable to NIST SRM • High-quality offering accurate titer determinations • Accompanied by a certificate of analysis (CoA) |
| General description: | Search & download your certificate here. ![]() |
| General description: | Trizma® base is a volumetric standard produced under rigorous conditions and measured with the highest possible precision. Its content is determined by volumetric neutralization titration using a combined pH glass electrode. The certified value and uncertainty measurement of the standard are in accordance with ISO Guide 35. |
| Legal Information: | Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Other Notes: | The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution. For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | >99.5% |
| bp | 219-220 °C/10 mmHg (lit.) |
| mp | 167-172 °C (lit.) |
| UNSPSC | 41116107 |

