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L-Ascorbic acid

SIAL/95212 - tested according to Ph. Eur.

Synonym: Acidum ascorbicum; L-Threoascorbic acid; Antiscorbutic factor; Vitamin C

CAS Number: 50-81-7
Empirical Formula (Hill Notation): C6H8O6
Molecular Weight: 176.12
EC Number: 200-066-2
MDL Number: MFCD00064328
Linear Formula: C6H8O6
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-95212-250G 250 g
$225.00
1/EA
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45-95212-1KG 1 kg
$440.00
1/EA
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agency tested according to Ph. Eur.
  USP/NF
assay 99.0-100.5%
biological source synthetic
color white to off-white
form solid
InChI 1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
InChI key CIWBSHSKHKDKBQ-JLAZNSOCSA-N
mp 190-194 °C (dec.)
pH 1.0-2.5 (25 °C, 176 g/L in water)
Quality Level 200 
SMILES string OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O
solubility water: soluble 176 g/L at 20 °C
Application:

  • Targeted screening of multiple anti-inflammatory components from Chrysanthemi indici Flos by ligand fishing with affinity UF-LC/MS: This study investigates the application of L-Ascorbic acid in enhancing the screening of anti-inflammatory compounds, utilizing its properties to stabilize reactive samples in cell cultures (Huang et al., 2024 ).

  • Phenolic Content, Antioxidant Potential, and Antimicrobial Activity of Uvaria chamae (Annonaceae), a Food Plant from Burkina Faso: Demonstrates the use of L-Ascorbic acid in the evaluation of antioxidant properties of plant extracts, which is crucial in the pharmaceutical research of natural products (Kabore et al., 2024 ).

Biochem/physiol Actions: L-Ascorbic acid functions according to its oxido-reduction property. It is a co-factor for hydroxylation. The biochemical actions of L-ascorbic acid is dependent on the activity of monoxygenase. It is involved in carnitine, collagen synthesis and production of neurotransmitters. Vitamin C exhibits anti-oxidant properties. Vitamin C plays a role in providing protection against photoaging and anti-aging effect. Deficiency of vitamin C leads to scurvy, bleeding gums, poor wound healing, anemia and muscle degeneration.
Biochem/physiol Actions: Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates.
General description: L-Ascorbic acid is the most biologically active form of ascorbic acid. It is hydrophilic and an unstable compound. L-Ascorbic acid contains a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid, also referred to as Vitamin C, is a water-soluble vitamin. Ascorbic acid carries a neutral charge, which gets converted to ascorbate by protonation. Vitamin C is a part of citrus fruits, such as broccoli, strawberries, turnip.
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity 99.0-100.5%
mp 190-194 °C (dec.)
UNSPSC 12352205

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