Poly(ethylene glycol)

SIAL/96699 - analytical standard, for GPC, 40,000

Synonym: PEG

CAS Number: 25322-68-3
MDL Number: MFCD00081839
Linear Formula: H(OCH₂CH₂)_nOH
Product Type: Chemical

application(s)	cleaning products cosmetics food and beverages personal care
format	neat
grade	analytical standard
	for GPC
InChI	1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key	LYCAIKOWRPUZTN-UHFFFAOYSA-N
M_w/M_n	~1.14
mol wt	M_n ~36500
	M_p ~40000
	M_w ~41500
Quality Level	100
shelf life	limited shelf life, expiry date on the label
SMILES string	C(CO)O
storage temp.	2-8°C
technique(s)	gel permeation chromatography (GPC): suitable

Application:

Poly(ethylene glycol) in biomaterials synthesis: Research showcases the development of disulfide-cross-linked tetra-PEG gels, highlighting the utility of poly(ethylene glycol) in creating advanced biomaterials that are biocompatible and functional for various biomedical applications (Meng et al., 2024 ).

PEGylation reagents for drug delivery: PEG is employed in the formation of hybrid polymersomes for mRNA delivery, demonstrating its critical role in enhancing the stability and cellular uptake of therapeutic agents, thereby improving treatment efficacy and safety (Shin et al., 2024 ).

Polyethylene glycol for organic synthesis: PEG is used in solvent-free sample preparations for MALDI-TOF MS of polymer blends, facilitating cleaner and more environmentally friendly processes in polymer analysis and characterization (Dalgic and Weidner, 2024 ).

PEG reagents for protein modification: PEG-based block copolymers are synthesized for drug delivery applications, where PEGylation significantly increases the solubility and stability of therapeutic molecules, enhancing their pharmacological profiles (Parcero-Bouzas et al., 2024 ).

Poly(ethylene glycol) in biotechnology: PEG is integrated into bioplastic formulations to improve the crystallization, thermal, and mechanical properties of poly(L-lactide) bioplastics, underscoring its versatility and importance in developing sustainable materials (Pakkethati et al., 2024 ).

General description:

Poly(ethylene glycol) is a nontoxic and non-biodegradable polymer, which can find applications in drug delivery systems.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	281.5 °F - closed cup
Flash Point(C)	138.6 °C - closed cup

Storage Temp.	2-8°C
UNSPSC	12352104