Alfacalcidol

SIAL/A0325450 - European Pharmacopoeia (EP) Reference Standard

Synonym: 1α-Hydroxyvitamin D₃; 1α-Hydroxycholecalciferol; Alfacalcidol

CAS Number: 41294-56-8
Empirical Formula (Hill Notation): C₂₇H₄₄O₂
Molecular Weight: 400.64
MDL Number: MFCD00868328
Linear Formula: C₂₇H₄₄O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-A0325450-3EA	3 ea	$0.00 1/EA CALL FOR PRICE		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

agency	EP
application(s)	pharmaceutical (small molecule)
biological source	synthetic
form	solid
format	neat
grade	pharmaceutical primary standard
InChI	1S/C27H44O2/c1-18(2)8-6-9-19(3)24-13-14-25-21(10-7-15-27(24,25)5)11-12-22-16-23(28)17-26(29)20(22)4/h11-12,18-19,23-26,28-29H,4,6-10,13-17H2,1-3,5H3/b21-11+,22-12-/t19-,23-,24-,25+,26+,27-/m1/s1
InChI key	OFHCOWSQAMBJIW-AVJTYSNKSA-N
manufacturer/tradename	EDQM
Quality Level	100
SMILES string	CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2C(CCC[C@]12C)=CC=C3C[C@@H](O)C[C@H](O)C3=C
storage temp.	−20°C
technique(s)	gas chromatography (GC): suitable
	liquid chromatography (LC): suitable

Application:	Alfacalcidol may be used as an analytical reference standard for the quantification of the analyte in bulk and tablet dosage forms using spectrophotometric technique.
Biochem/physiol Actions:	Synthetic vitamin D₃ analog that is metabolized to 1,25-dihydroxycholecalciferol. Inhibits bone resorption and stimulates bone formation. Supresses parathyroid hormone secretion by bovine parathyroid cells.
Caution:	Please find SDS provided by EDQM here. .
General description:	This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the authority of the issuing pharmacopoeia. For further information and support please go to the website of the issuing pharmacopoeia. Alfacalcidol is an active metabolite of vitamin D, used as a vitamin supplement due to it longer half-life. It is found to be effective in regulating calcium balance/bone metabolism.
Other Notes:	Sales restrictions may apply.
Packaging:	Unit quantity: 15 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue .

Symbol	GHS06
Signal word	Danger
Hazard statements	H300
Precautionary statements	P301 + P310 + P330
RIDADR	UN 2811 6.1 / PGI
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	−20°C
UNSPSC	41116107

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