Albendazole
SIAL/A4673 - analytical standard, ≥98%
Synonym: Methyl 5-
CAS Number: 54965-21-8
Empirical Formula (Hill Notation): C12H15N3O2S
Molecular Weight: 265.33
EC Number: 259-414-7
MDL Number: MFCD00083232
Linear Formula: C12H15N3O2S
Product Type: Chemical
| application(s) | forensics and toxicology pharmaceutical (small molecule) |
| assay | ≥98% |
| format | neat |
| grade | analytical standard |
| InChI | 1S/C12H15N3O2S/c1-3-6-18- |
| InChI key | HXHWSAZORRCQMX-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | CCCSc1ccc2[nH]c(NC(=O)OC) |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Application: | Albendazole may be used as a reference standard for the determination of albendazole and its major metabolites, albendazole sulphoxide and albendazole sulphone by high-performance liquid chromatography (HPLC) method in mice plasma. |
| Application: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
| Biochem/physiol Actions: | Binds to tubulin and inhibits microtubule assembly. |
| General description: | Albendazole is a benzimidazole derivative used for the treatment of human gastrointestinal helmintiasis. It inhibits microtubule and blocks the glucose uptake that causes depletion of glycogen stores and lowering formation of adinosine triphosphate (ATP) in the larval and adult stages of susceptible parasite. |
| General description: | Chemical structure: benzimidazole |
| Other Notes: | Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. A4673.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin. |
| Packaging: | 10 g in poly bottle |
| Symbol |   GHS08,GHS09 |
| Signal word | Warning |
| Hazard statements | H361d - H373 - H410 |
| Precautionary statements | P201 - P202 - P260 - P273 - P280 - P308 + P313 |
| Hazard Codes | Xn |
| Risk Statements | 63-48/22 |
| Safety Statements | 36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% |
| UNSPSC | 41116107 |