Aztreonam
SIAL/A6848 - analytical standard
Synonym: [2S-[2α,3β(Z)]]-2-[[[1-(2-Amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid
CAS Number: 78110-38-0
Empirical Formula (Hill Notation): C13H17N5O8S2
Molecular Weight: 435.43
EC Number: 278-839-9
MDL Number: MFCD00072145
Linear Formula: C13H17N5O8S2
Product Type: Chemical
| application(s) | forensics and toxicology pharmaceutical (small molecule) veterinary |
| form | powder or crystals |
| grade | analytical standard |
| InChI | 1S/C13H17N5O8S2/c1-5-7(10 |
| InChI key | WZPBZJONDBGPKJ-VEHQQRBSSA |
| Quality Level | 100  |
| SMILES string | C[C@H]1[C@H](NC(=O)C(=N/ |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Application: | The analytical standard can be used as follows:• Determination of aztreonam in two simulated lung fluid solutions― artificial lysosomal fluid and gamble solution by a UV spectroscopic method • Multi-residue analysis of eight β-lactams by ultra-high performance liquid chromatography (UHPLC) combined with a photo-diode array (PDA) detector in human plasma & serum samples • Simultaneous quantitative analysis of nine β-lactams by UHPLC along with tandem mass spectrometry (MS/MS) in human plasma samples |
| General description: | Aztreonam belongs to the group of monocyclic β-lactam antibiotics, isolated from Chromobacterium violaceum. It is used against gram-negative bacterial infections, such as infections of the bladder, kidneys, bone, and urinary tract. It acts by binding to the penicillin-binding protein-3 (PBP3) and inhibiting the synthesis of bacterial cell walls causing cell lysis and death. |
| Other Notes: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
| Packaging: | 50 mg in glass insert |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 41116107 |