Acetaminophen

SIAL/A7085 - BioXtra, ≥99.0%

Synonym: 4′-Hydroxyacetanilide; 4-Acetamidophenol; N-(4-Hydroxyphenyl)acetamide; N-Acetyl-4-aminophenol; APAP; Paracetamol

CAS Number: 103-90-2
Empirical Formula (Hill Notation): C₈H₉NO₂
Molecular Weight: 151.16
EC Number: 203-157-5
MDL Number: MFCD00002328
Linear Formula: CH₃CONHC₆H₄OH
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-A7085-100G	100 g	$53.20 1/EA	Add To Favorites
45-A7085-500G	500 g	$187.00 1/EA	Add To Favorites
45-A7085-1KG	1 kg	$321.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A7085-1KG

Properties
Descriptions
Safety Info.
Basic Data

anion traces	chloride (Cl^-): ≤0.05%
	sulfate (SO₄^2-): ≤0.05%
assay	≥99.0%
cation traces	Al: ≤0.0005%
	Ca: ≤0.0005%
	Cu: ≤0.0005%
	Fe: ≤0.0005%
	K: ≤0.005%
	Mg: ≤0.0005%
	Na: ≤0.005%
	NH₄⁺: ≤0.05%
	Pb: ≤0.001%
	Zn: ≤0.0005%
form	powder
ign. residue	≤0.1%
impurities	≤0.0005% Phosphorus (P)
	≤0.1% Insoluble matter
InChI	1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)
InChI key	RZVAJINKPMORJF-UHFFFAOYSA-N
mp	168-172 °C (lit.)
product line	BioXtra
Quality Level	200
SMILES string	CC(=O)Nc1ccc(O)cc1
solubility	ethanol: 0.5 M, clear, colorless

Application:	Acetaminophen has been used: • as an anti-inflammatory drug to test its effect in lipid peroxidation in marine mussels • to test its effect on neurite outgrowth in gamma-aminobutyric acid-ergic and glutamatergic neurons • as a hepatocellular injury inducing agent in mice
Application:	Analgesic.
Biochem/physiol Actions:	Acetaminophen or paracetamol is an inhibitor of prostaglandin synthesis. It is complexed with arachidonic acid in central nervous system resulting in the formation of N-arachidonoylphentolamine, which is essential for the activation of cannabinoid receptor. Acetaminophen is metabolized to toxic N-acetyl-p-benzoquinone imine. Paracetamol is prescribed for osteoarthritis pain and inhibits cyclooxygenase 1 and 2 activities. It is metabolized by the cytochrome P450 enzymes in liver and is implicated in liver toxicity.
General description:	Acetaminophen or paracetamol is an analgesic and antipyretic. It is however a weak non opioid analgesic.
Packaging:	1 kg in glass bottle
Packaging:	100, 500 g in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
Precautionary statements	P264 - P270 - P301 + P312 - P501
Hazard Codes	Xn
Risk Statements	22-36/37/38
Safety Statements	26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	364.3 °F - Pensky-Martens c
Flash Point(C)	184.6 °C - Pensky-Martens c

Purity	≥99.0%
mp	168-172 °C (lit.)
UNSPSC	12352200

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