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(+)-PSI Reagent

SIAL/ALD00604 - 95%

Synonym: (+)-Ψ; (2R,3aR,6S,7aR)-3a-Methyl-2-((perfluorophenyl)thio)-6-(prop-1-en-2-yl)hexahydrobenzo[d][1,3,2]oxathiaphosphole 2-sulfide; Phosphorus-Sulfur Incorporation Reagent

CAS Number: 2245335-71-9
Empirical Formula (Hill Notation): C16H16F5OPS3
Molecular Weight: 446.46
Linear Formula: C16H16F5OPS3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-ALD00604-500MG 500 mg
 $198.00
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45-ALD00604-5G 5 g
 $460.00
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45-ALD00604-25G 25 g
 $1570.00
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45-ALD00604-100G 100 g
 $4660.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: ALD00604-500MG.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: ALD00604-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: ALD00604-5G

 

assay 95%
form powder or crystals
mp 102-107 °C
Application: Air- and moisture-tolerant, this (+)-PSI Reagent was developed in the Baran  lab for stereocontrolled synthesis of phosphorothioate oligonucleotides. The enantiomer, (−)-PSI Reagent, is also available (cat# ALD00602 ).
The PSI Reagents open access to thiophosphate-based nucleotide molecules with therapeutic promise as demonstrated by the Baran  lab in the preparation of pure stereoisomers of cyclic dinucleotides (CDNs) and antisense oligonucleotides (ASOs).
Legal Information: PCT/US2019/027256; U.S. Nonprovisional Patent Application #16/382,692
Other Notes: Unlocking P(V): Reagents for chiral phosphorothioate synthesis 

PSI on OpenFlask 
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity 95%
mp 102-107 °C
UNSPSC 12352101

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