Betamethasone

SIAL/B1000000 - European Pharmacopoeia (EP) Reference Standard

Synonym: 9α-Fluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione; 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione; 9α-Fluoro-16β-methylprednisolone

CAS Number: 378-44-9
Empirical Formula (Hill Notation): C₂₂H₂₉FO₅
Molecular Weight: 392.46
MDL Number: MFCD00062969
Linear Formula: C₂₂H₂₉FO₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-B1000000	60 mg	$220.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

agency	EP
API family	betamethasone
application(s)	pharmaceutical (small molecule)
biological source	synthetic
color	white
density	0.305 g/cm³ at 25 °C (77°F)
format	neat
grade	pharmaceutical primary standard
InChI	1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
InChI key	UREBDLICKHMUKA-DVTGEIKXSA-N
manufacturer/tradename	EDQM
mp	235-237 °C (lit.)
	235.6 °C (456.1°F at 1013.0 hPa)
packaging	pkg of 60 mg
shipped in	ambient
SMILES string	[H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C
solubility	water: slightly soluble 0.063 g/L at 37 °C
storage condition	protect from light
storage temp.	2-8°C

Application:	Betamethasone EP reference standard may be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques.
General description:	Betamethasone, a synthetic glucocorticoid, belongs to the corticosteroid family of active pharmaceutical ingredients (APIs). This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes:	Sales restrictions may apply.
Packaging:	The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue .

Symbol	GHS08
Signal word	Danger
Hazard statements	H360FD - H373
Precautionary statements	P202 - P260 - P280 - P308 + P313 - P405 - P501
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

mp	235-237 °C (lit.); 235.6 °C (456.1°F at 1013.0 hPa)
Density	0.305 g/cm³ at 25 °C (77°F)
Storage Temp.	2-8°C
UNSPSC	41116107

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