Adapalene
SIAL/BP1120 - British Pharmacopoeia (BP) Reference Standard
Synonym: 6-
CAS Number: 106685-40-9
Empirical Formula (Hill Notation): C28H28O3
Molecular Weight: 412.52
MDL Number: MFCD03106112
Linear Formula: C28H28O3
Product Type: Chemical
format | neat |
grade | pharmaceutical primary standard |
InChI | 1S/C28H28O3/c1-31-26-7-6- |
InChI key | LZCDAPDGXCYOEH-AADAIPAGSA |
manufacturer/tradename | BP |
SMILES string | COc1ccc(cc1C23C[C@H]4C[C@ |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Retinoic acid analogue that is a RARβ and RARγ agonist (AC50 values are 2.2, 9.3, 22 and > 1000 nM for RARβ, RARγ, RARα and RXRα receptors respectively). Inhibits proliferation and induces apoptosis in colorectal cancer cells in vitro. Displays comedolytic activity. Its unique pharmacological properties make it superior to other retinoids for the treatment of acne. |
General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. |
Other Notes: | Sales restrictions may apply. |
Packaging: | Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia ![]() ![]() |
RIDADR | NONH for all modes of transport |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-8°C |
UNSPSC | 41116107 |