Dexamethasone

SIAL/BP578 - British Pharmacopoeia (BP) Assay Standard

Synonym: (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione; 9α-Fluoro-16α-methylprednisolone; Prednisolone F

CAS Number: 50-02-2
Empirical Formula (Hill Notation): C₂₂H₂₉FO₅
Molecular Weight: 392.46
EC Number: 200-003-9
MDL Number: MFCD00064136
Linear Formula: C₂₂H₂₉FO₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-BP578	100 mg	$255.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

API family	dexamethasone
application(s)	pharmaceutical pharmaceutical small molecule
form	solid
format	neat
grade	pharmaceutical primary standard
InChI	1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
InChI key	UREBDLICKHMUKA-CXSFZGCWSA-N
manufacturer/tradename	BP
mp	262-264 °C (lit.)
shelf life	limited shelf life, expiry date on the label
SMILES string	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
storage temp.	2-8°C

Application:	Dexamethasone BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia. Also used in monographs such as: Tobramycin and Dexamethasone Eye Drops, Suspension • Dexamethasone Sodium Phosphate Oral Solution • Hydrocortisone Sodium Succinate Injection • Prednisolone Tablets • Dexamethasone Eye Drops, Suspension • Dexamethasone Sodium Phosphate Eye Drops, Solution • Dexamethasone and Neomycin Ear Spray • Betamethasone Tablets • Dexamethasone Tablets
Biochem/physiol Actions:	Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.
General description:	This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes:	Sales restrictions may apply.

Symbol	GHS08
Signal word	Danger
Hazard statements	H360FD
Precautionary statements	P201 - P202 - P280 - P308 + P313 - P405 - P501
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

mp	262-264 °C (lit.)
Storage Temp.	2-8°C
UNSPSC	41116107

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