Meptazinol hydrochloride
SIAL/BP583 - British Pharmacopoeia (BP) Reference Standard
Synonym: 3-
CAS Number: 59263-76-2
Empirical Formula (Hill Notation): C15H23NO· HCl
Molecular Weight: 269.81
EC Number: 261-683-0
MDL Number: MFCD00941476
Linear Formula: C15H23NO· HCl
Product Type: Chemical
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C15H23NO.ClH/c1-3-15(9 |
| InChI key | MPJUSISYVXABBH-UHFFFAOYSA |
| manufacturer/tradename | BP |
| quality | British Pharmacopoeia (BP) Reference Standard |
| SMILES string | Cl.CCC1(CCCCN(C)C1)c2cccc |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | Meptazinol entered the human pharmaceutical market as a racemic mixture in the 1980s for use as an analgesic. Its pharmacology is not completely understood; however, its analgesic properties are mostly due to its partial agonism at the mu1 opioid receptor. Due to its partial agonism, Meptazinol antagonizes morphine dependence in vivo. Its advantage over other opiates is its reduced capacity to cause addition and respiratory depression, also due to its intrinsic activity as a partial agonist. Meptazinol has been found to have additional activity as an acetylcholinesterase (AChE) inhibitor, particularly in its (-) enantiomeric form, which may partially explain its analgesic properties. AChE inhibitors are used to treat Alzheimer′s disease, providing additional interest in this compound. |
| General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia. |
| Other Notes: | Sales restrictions may apply. |
| Packaging: | Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia   |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264 - P270 - P301 + P312 + P330 - P501 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 41116107 |