Fluticasone propionate

SIAL/BP587 - British Pharmacopoeia (BP) Reference Standard

Synonym: (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid S-(fluoromethyl) ester

CAS Number: 80474-14-2
Empirical Formula (Hill Notation): C₂₅H₃₁F₃O₅S
Molecular Weight: 500.57
MDL Number: MFCD00866007
Linear Formula: C₂₅H₃₁F₃O₅S
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-BP587	100 mg	$229.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

API family	fluticasone
application(s)	pharmaceutical pharmaceutical small molecule
form	solid
format	neat
grade	pharmaceutical primary standard
InChI	1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1
InChI key	WMWTYOKRWGGJOA-CENSZEJFSA-N
manufacturer/tradename	BP
shelf life	limited shelf life, expiry date on the label
SMILES string	CCC(=O)O[C@@]1([C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)SCF
storage temp.	2-8°C

Application:	Fluticasone propionate BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia. Also used in monographs such as: Fluticasone and Salmeterol Inhalation Powder • Fluticasone and Salmeterol Inhalation Powder, pre-metered • Fluticasone Nasal Spray • Fluticasone and Salmeterol Pressurised Inhalation, Suspension • Fluticasone Pressurised Inhalation • Fluticasone Nasal Drops • Fluticasone Cream • Fluticasone Inhalation Powder • Fluticasone Ointment • Fluticasone Inhalation Powder, pre-metered
Biochem/physiol Actions:	Fluticasone propionate is a second generation glucocorticoid. Used as an anti-inflammatory agent for asthma. Shown to enhance eosinophil apoptosis in a concentration-dependent manner via the glucocorticoid receptor.
General description:	This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes:	Sales restrictions may apply.
Packaging:	Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	2-8°C
UNSPSC	41116107

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