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Sodium alendronate

SIAL/BP830 - British Pharmacopoeia (BP) Reference Standard

Synonym: Alendronate sodium trihydrate; 4-amino-1-hydroxy-1-phosphonobutyl phosphonic acid, monosodium; MK-217

CAS Number: 121268-17-5
Empirical Formula (Hill Notation): C4H12NaNO7P2 · 3 H2O
Molecular Weight: 325.12
MDL Number: MFCD01748233
Linear Formula: C4H12NaNO7P2 · 3 H2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-BP830 100 mg
 $229.00
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API family alendronate
application(s) pharmaceutical
pharmaceutical small molecule
form solid
format neat
grade pharmaceutical primary standard
InChI 1S/C4H13NO7P2.Na.3H2O/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;;;;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);;3*1H2/q;+1;;;/p-1
InChI key DCSBSVSZJRSITC-UHFFFAOYSA-M
manufacturer/tradename BP
quality British Pharmacopoeia (BP) Reference Standard
shelf life limited shelf life, expiry date on the label
SMILES string [Na+].[H]O[H].[H]O[H].[H]O[H].NCCCC(O)(P(O)(O)=O)P(O)([O-])=O
storage temp. 2-8°C
Application: Sodium alendronate BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Alendronic Acid and Colecalciferol Tablets
    • Alendronic Acid Tablets
    		•
    Biochem/physiol Actions: Alendronate sodium trihydrate is a bone resorption inhibitor; farnesyl diphosphate synthase inhibitor (IC50 = 460 nM); CD45 protein tyrosine phosphatase inhibitor.
    General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
    Other Notes: Sales restrictions may apply.
    Packaging: Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia 
    Symbol GHS07  GHS07
    Signal word Warning
    Hazard statements H302
    Precautionary statements P264 - P270 - P301 + P312 + P330 - P501
    RIDADR NONH for all modes of transport
    WGK Germany WGK 3
    Flash Point(F) Not applicable
    Flash Point(C) Not applicable
    Storage Temp. 2-8°C
    UNSPSC 41116107

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