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Losartan potassium

SIAL/BP867 - British Pharmacopoeia (BP) Reference Standard

Synonym: 2-Butyl-4-chloro-1-{[2′-(1H-tetrazol-5-yl)(1,1′-biphenyl)-4-yl]methyl}-1H-imidazole-5-methanol monopotassium salt; 2-butyl-4-chloro-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]- 1H-Imidazole-5-methanol potassium salt; DuP 753; MK 954; Potassium 5-(4′-((2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl)methyl)-[1,1′-biphenyl]-2-yl)tetrazol-1-ide

CAS Number: 124750-99-8
Empirical Formula (Hill Notation): C22H22ClKN6O
Molecular Weight: 461.00
MDL Number: MFCD02092704
Linear Formula: C22H22ClKN6O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-BP867 150 mg
 $257.00
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API family losartan
application(s) pharmaceutical
pharmaceutical small molecule
form solid
format neat
grade pharmaceutical primary standard
InChI 1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1
InChI key OXCMYAYHXIHQOA-UHFFFAOYSA-N
manufacturer/tradename BP
shelf life limited shelf life, expiry date on the label
SMILES string CCCCc1nc(Cl)c(CO)n1Cc2ccc(cc2)-c3ccccc3-c4nnnn4[K]
storage temp. 2-8°C
Application: Losartan potassium BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Losartan Potassium Tablets
    		•
    Biochem/physiol Actions: Losartan potassium is an orally available, potent, and selective competitive angiotensin II receptor type 1 (AT1) antagonist. Losartan potassium is used for treatment of hypertension.
    General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
    Other Notes: Sales restrictions may apply.
    Packaging: Unit quantity: 150 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia 
    RIDADR NONH for all modes of transport
    WGK Germany WGK 3
    Flash Point(F) Not applicable
    Flash Point(C) Not applicable
    Storage Temp. 2-8°C
    UNSPSC 41116107

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