Caffeine
SIAL/C0750 - powder, ReagentPlus®
Synonym: 1,3,7-
CAS Number: 58-08-2
Empirical Formula (Hill Notation): C8H10N4O2
Molecular Weight: 194.19
EC Number: 200-362-1
MDL Number: MFCD00005758
Linear Formula: C8H10N4O2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: C0750-100G
This image depicts SKU: C0750-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: C0750-500G
This image depicts SKU: C0750-500G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: C0750-1KG
This image depicts SKU: C0750-1KG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: C0750-5G
This image depicts SKU: C0750-5G
| form | powder |
| InChI | 1S/C8H10N4O2/c1-10-4-9-6- |
| InChI key | RYYVLZVUVIJVGH-UHFFFAOYSA |
| mp | 234-236.5 °C (lit.) |
| product line | ReagentPlus® |
| Quality Level | 200  |
| SMILES string | CN1C(=O)N(C)c2ncn(C)c2C1= |
| solubility | H2O: 15 mg/mL |
| Application: | Caffeine has been used: • to study its impact on the fluorescence of Petunia nuclei • as a stimulant to induce c-fos expression in rodents • as a component of defined media for the development of bovine oocytes in vitro |
| Biochem/physiol Actions: | A central nervous system stimulant believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3′,5′-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. Thus, levels of cAMP increase in cells following treatment with caffeine. It has been reported to affect cellular calcium levels, releasing calcium from intracellular stores. It overrides the cell cycle effects of various chemicals such as protease inhibitors, preventing apoptosis; and it has been shown to inhibit cellular DNA repair mechanisms. |
| Caution: | Keep tightly sealed. |
| General description: | Caffeine is a widely ingested pharmacologically active substance. It belongs to the class of methylxanthines. It is a naturally occurring alkaloid found in coffee, cocoa and other plants. Caffeine might be associated with osteoporosis, cardiovascular risk, arrhythmia and gastrointestinal disturbances. Caffeine is used to treat orthostatic hypotension, bronchopulmonary dysplasia and apnea of prematurity (AOP). |
| Legal Information: | ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 5, 100, 500 g in poly bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P301 + P312 + P330 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 234-236.5 °C (lit.) |
| UNSPSC | 12352210 |