Cholecalciferol for system suitability
SIAL/C2150000 - European Pharmacopoeia (EP) Reference Standard
Synonym: Cholecalciferol; (+)-Vitamin D3; 7-Dehydrocholesterol activated; Activated 7-dehydrocholesterol; Calciol
CAS Number: 67-97-0
Empirical Formula (Hill Notation): C27H44O
Molecular Weight: 384.64
MDL Number: MFCD00078131
Linear Formula: C27H44O
Product Type: Chemical
| agency | EP |
| application(s) | pharmaceutical (small molecule) |
| biological source | synthetic |
| form | solid |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C27H44O/c1-19(2)8-6-9- |
| InChI key | QYSXJUFSXHHAJI-YRZJJWOYSA |
| manufacturer/tradename | EDQM |
| mp | 83-86 °C (lit.) |
| SMILES string | CC(C)CCC[C@@H](C)[C@@]1([ |
| storage temp. | −20°C |
| technique(s) | gas chromatography (GC): suitable |
| liquid chromatography (LC): suitable |
| Application: | Cholecalciferol for system suitability may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography. |
| Biochem/physiol Actions: | Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis. |
| Caution: | Please find SDS provided by EDQM here.   . |
| General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia . Cholecalciferol, also referred to as vitamin D3, promotes the absorption of calcium and phosphorus in the body to regulate bone growth. It is most commonly found in humans and animals and is produced in our skin when exposed to sunlight. It is used to treat and prevent bone disorders (such as rickets, osteomalacia). |
| Other Notes: | Sales restrictions may apply. |
| Packaging: | Unit quantity: 1 mL. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue . |
| Symbol |   GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H300 + H310 + H330 - H372 |
| Precautionary statements | P260 - P262 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P314 |
| RIDADR | UN 2811 6.1 / PGII |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 83-86 °C (lit.) |
| Storage Temp. | −20°C |
| UNSPSC | 41116107 |