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Clobetasone butyrate

SIAL/C5548 - ≥98%

Synonym: 21-Chloro-9-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,11,20-trione 17-butyrate

CAS Number: 25122-57-0
Empirical Formula (Hill Notation): C26H32ClFO5
Molecular Weight: 478.98
EC Number: 246-635-9
MDL Number: MFCD00133196
Linear Formula: C26H32ClFO5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-C5548-100MG 100 mg
 $61.90
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: C5548-100MG

 

ε (extinction coefficient) 13.4 at 243 nm in chloroform
application(s) diagnostic assay manufacturing
hematology
histology
assay ≥98%
color white to faint yellow cast
form powder
InChI 1S/C26H32ClFO5/c1-5-6-22(32)33-26(21(31)14-27)15(2)11-19-18-8-7-16-12-17(29)9-10-23(16,3)25(18,28)20(30)13-24(19,26)4/h9-10,12,15,18-19H,5-8,11,13-14H2,1-4H3/t15-,18-,19-,23-,24-,25-,26-/m0/s1
InChI key FBRAWBYQGRLCEK-AVVSTMBFSA-N
mp 90-100 °C
Quality Level 200 
SMILES string CCCC(=O)O[C@@]1([C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)C(=O)C[C@]12C)C(=O)CCl
solubility chloroform: 50 mg/mL, clear, faintly yellow
storage temp. room temp
Application: Clobetasone butyrate has been used as an internal standard for the quantitative assay of clobetasol propionate.
Application: Clobetasone butyrate has been used to analyze its bio-concentration factor (BCF) in Cyprinus carpio.
Biochem/physiol Actions: Clobetasone butyrate is a potent topical corticosteroid and is primarily used to treat atopic dermatitis (AD). Low dosage of this drug is used to treat dry eye in Sjogrens syndrome.
General description: Clobetasone butyrate is a corticosteroid.
Packaging: 100 mg in poly bottle
Symbol GHS08  GHS08
Signal word Warning
Hazard statements H351
Precautionary statements P281
Hazard Codes Xn
Risk Statements 40
Safety Statements 22-36
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98%
mp 90-100 °C
Storage Temp. room temp
UNSPSC 12171500

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