Dimethyl sulfoxide
SIAL/D1435 - meets EP testing specifications, meets USP testing specifications
Synonym: DMSO
CAS Number: 67-68-5
Empirical Formula (Hill Notation): C2H6OS
Molecular Weight: 78.13
EC Number: 200-664-3
MDL Number: MFCD00002089
Linear Formula: (CH3)2SO
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D1435-1L.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D1435-500ML.
| agency | meets EP testing specifications |
| meets USP testing specifications | |
| assay | ≥99.5% |
| autoignition temp. | 573 °F |
| bp | 189 °C (lit.) |
| color | colorless |
| density | 1.10 g/mL (lit.) |
| 1.100-1.104 g/mL at 25 °C (relative density (EP)) | |
| expl. lim. | 42 %, 63 °F |
| form | liquid |
| impurities | ≤0.1% water (Karl Fischer, USP) |
| ≤0.2% water (Karl Fischer, EP) | |
| InChI | 1S/C2H6OS/c1-4(2)3/h1-2H3 |
| InChI key | IAZDPXIOMUYVGZ-UHFFFAOYSA |
| mp | 16-19 °C (lit.) |
| Quality Level | 200  |
| refractive index | n |
| n |
|
| SMILES string | CS(C)=O |
| solubility | H2O: miscible (completely) |
| technique(s) | cryopreservation: suitable |
| UV absorption | λ: 285 nm Amax: ≤0.20 |
| λ: 295 nm Amax: ≤0.20 | |
| vapor density | 2.7 (vs air) |
| vapor pressure | 0.42 mmHg ( 20 °C) |
| Application: | Dimethyl sulfoxide has been used: • for the dissolution of tetramethylrhodamine dye, which is used as fluorophore for fluorescence in- situ hybridization (FISH) experiments • as a control in indirect immunofluorescent assay (IFA) of swine testicular (ST) cells • for the suspension and separation of buccal cells • a polar aprotic solvent used in polymerase chain reactions (PCR) and as a cryoprotectant vitrification agent for the preservation of cells, tissues and organs. |
| Biochem/physiol Actions: | Dimethyl sulfoxide (DMSO) is a low molecular weight, less hydrophilic and a freely permeable cryoprotectant. It is a polar aprotic solvent used in polymerase chain reactions (PCR) and as a cryoprotectant and vitrification agent for the preservation of cells, tissues and organs. |
| Caution: | Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product. |
| Other Notes: | For information on dimethyl sulfoxide miscibility, please visit the following link: Dimethyl Sulfoxide Miscibility/Immiscibility Table |
| Packaging: | 1 L in glass bottle |
| Packaging: | 500 mL in glass bottle |
| RIDADR | NA 1993 / PGIII |
| WGK Germany | WGK 1 |
| Flash Point(F) | 188.6 °F - closed cup |
| Flash Point(C) | 87 °C - closed cup |
| Purity | ≥99.5% |
| bp | 189 °C (lit.) |
| mp | 16-19 °C (lit.) |
| Density | 1.100-1.104 g/mL at 25 °C (relative density (EP)); 1.10 g/mL (lit.) |
| Refractive Index | n |
| UNSPSC | 12191502 |