Doxorubicin hydrochloride

SIAL/D2975000 - European Pharmacopoeia (EP) Reference Standard

Synonym: DOX; Hydroxydaunorubicin hydrochloride

CAS Number: 25316-40-9
Empirical Formula (Hill Notation): C₂₇H₂₉NO₁₁ · HCl
Molecular Weight: 579.98
EC Number: 246-818-3
MDL Number: MFCD00077757
Linear Formula: C₂₇H₂₉NO₁₁ · HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-D2975000	150 mg	$220.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

API family	doxorubicin
application(s)	pharmaceutical (small molecule)
format	neat
grade	pharmaceutical primary standard
InChI	1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1
InChI key	MWWSFMDVAYGXBV-RUELKSSGSA-N
manufacturer/tradename	EDQM
mp	216 °C (dec.) (lit.)
SMILES string	Cl[H].COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO

Application:	This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia. Their suitability for any other use is not guaranteed and is the sole responsibility of the user. This standard is not intended for human or animal use. Established for the preparation of the below-given solutions as per European Pharmacopoeia: • Reference solutions (b) and (c) in the testing of related substances in daunorubicin hydrochloride using liquid chromatography (General text 2.2.29), according to the monograph 0662 • Reference solutions (a) and (c) to test related substances in doxorubicin hydrochloride using liquid chromatography (General text 2.2.29), according to the monograph 0714 • Reference solutions (b) and (c) in the testing of related substances in epirubicin hydrochloride using liquid chromatography (General text 2.2.29), according to the monograph 1590
General description:	This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia . Produced by certain strains of Streptomyces coeruleorubidus or Streptomyces peucetius or obtained by any other means.
Other Notes:	Sales restrictions may apply.
Packaging:	The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue .

Symbol	GHS07,GHS08
Signal word	Danger
Hazard statements	H302 - H340 - H350 - H360FD
Precautionary statements	P201 - P202 - P264 - P270 - P301 + P312 - P308 + P313
Hazard Codes	T,Xi
Risk Statements	45-22-36/38
Safety Statements	53-45
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

mp	216 °C (dec.) (lit.)
UNSPSC	41116107

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